Objective: To investigate body fluids of patients with undiagnosed leukodystrophies using in vitro 1H-NMR spectroscopy (H-NMRS). Methods: We conducted a cross-sectional study using high-resolution ...

Objective: The ascending reticular activating system (ARAS) modulates circadian wakefulness, which is preserved in a persistent vegetative state (PVS). Its metabolism is preserved. Impairment of ...

Background: Although cognitive dysfunction affects a relevant portion of patients with multiple sclerosis (MS), its pathologic substrate has not been clarified and it does not seem entirely ...

Background and Purpose Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an inherited disease due to cerebral microangiopathy presenting with ...

Objective: Motor impairment after stroke has been related to infarct size, infarct location, and integrity of motor tracts. To determine the value of diffusion tensor imaging (DTI) as a predictor of ...

Resumen Antecedentes: En pediatría la neuritis óptica generalmente se presenta después de un cuadro infeccioso, con edema de papila, que suele ser bilateral y tiene buen pronóstico. La conversión a ...

Objectives  To examine the effects of aerobic exercise on cognition and other biomarkers associated with Alzheimer disease pathology for older adults with mild cognitive impairment, and assess ...

Objective  To determine whether fluctuations in functional T-cell subsets can explain why multiple sclerosis (MS) relapses decline during pregnancy and increase in the postpartum period. ...

Objective  To determine the association between a composite measure of serological test results for common infections (Chlamydia pneumoniae, Helicobacter pylori, cytomegalovirus, and herpes ...

Do statins reduce the risk of vasospasm, delayed cerebral ischemia, and death after aneurysmal subarachnoid hemorrhage (SAH)? Two recent meta-analyses2,3 reach opposite conclusions. The 2008 ...

Objective: To investigate whether global and regional β-amyloid (Aβ) burden as measured with 11C Pittsburgh compound B (PIB) PET is associated with hippocampal atrophy characterized using ...

Objective: A consistently identified risk factor for Alzheimer disease (AD) is family history of dementia, with maternal transmission significantly more frequent than paternal transmission. A ...

Objective: To investigate whether cancer is associated with Alzheimer disease (AD) and vascular dementia (VaD). Methods: Cox proportional hazards models were used to test associations between ...

RESUMEN La hidrocefalia crónica del adulto (HCA), o hidrocefalia a presión normal, se caracteriza por una alteración de la marcha, una incontinencia de esfínteres y un deterioro cognitivo progresivo, ...

Objective: To test the hypothesis that lower 25-hydroxyvitamin D [25(OH)D] levels are associated with a greater likelihood of cognitive impairment and risk of cognitive decline. Methods: We ...