
OBJECTIVE: Vildagliptin is an orally active, potent and selective DPP-4 inhibitor that improves glycemic control in patients with type 2 diabetes by increasing alpha- and beta-cell responsiveness to ...
BACKGROUND: In type 2 diabetes mellitus there is a progressive loss of beta-cell function. One new approach yielding promising results is the use of the orally active dipeptidyl peptidase-4 (DPP-4) ...
Un nuevo estudio de imágenes cerebrales revela que una hormona del hambre, conocida por sus facultades para estimular el apetito, activa en realidad centros de recompensa claves en el cerebro para ...
SUMARIO:- Las embarazadas que presentan niveles de azúcar en sangre mayores a lo normal pero inferiores a los que indican la presencia de diabetes son más propensas que aquellas con menor cantidad de ...
Una nueva clase de fármacos para perder peso que suprime el apetito al bloquear los receptores cannabinoides en el cerebro debe ser usada con cuidado en los niños, según informan científicos de los ...
La obesidad causa la inflamación prolongada del tejido cardiaco lo que a su vez aumenta el riesgo de insuficiencia cardiaca, de acuerdo con un estudio de casi 7,000 personas. Se cree que los últimos ...
Treating diabetic patients with high LDL and hypertension to lower-than-normal targets appears to produce regressions in atherosclerosis not seen in similar patients treated to standard target LDL ...
The weight loss drug rimonabant (Acomplia, Sanofi-Aventis) has failed to show any benefit on progression of atherosclerosis in an intravascular ultrasound (IVUS) study in patients with abdominal ...
Remodeling of the resistance arteries is a hallmark of arterial hypertension and predicts cardiovascular events, but it was unknown whether it could also predict the blood pressure response to ...
We sought to define the contribution of each of the 2 kinin receptors (bradykinin 1 receptor [B1R] and bradykinin 2 receptor [B2R]) to the cardioprotection of angiotensin-converting enzyme (ACE) ...
Hypertension is associated with increased risk of cardiovascular diseases. Antihypertensive treatment, particularly blockade of the renin-angiotensin system, contributes to prevent ...
SUMMARY : - We studied 74 never-treated grade I hypertensive subjects aged 18 to 45 years and 20 normotensive control subjects to define the rate of increase in carotid intima-media thickness (IMT) ...
In adults, initial stages of hypertension are associated with elevated sympathetic drive and significant alterations in indirect autonomic markers. There is growing evidence that children in the ...
SUMMARY: - We assessed whether home blood pressure monitoring improved the prediction of progression of albuminuria when added to office measurements and compared it with ambulatory blood pressure ...
Essential hypertension is the most common diagnosis in US primary care settings for middle-aged persons and seniors. Yet, data on hypertension screening, treatment, and control in such settings are ...