Anales de Lípidos en Biología y Medicina
Número 46, 15 de Marzo de 2008
Contenido adicional
Noticias
- LIPIDS & OPHTHALMOLOGY : - The use of statins and the development of AMD in AREDS
Abstract Body: Purpose: To evaluate the association of statin use with incident advanced age-related macular degeneration (AMD) in patients enrolled in the Age-Related Eye Disease Study (AREDS). ...
- LIPIDS & CORONARY HEART DISEASE : - Effect of rosuvastatin therapy on coronary artery stenoses assessed by quantitative coronary angiography
Background Previous studies using quantitative coronary angiography have demonstrated that statin therapy slows the progression of coronary stenoses in proportion to average low-density lipoprotein ...
- LIPIDS : - Influence of apoA-V gene variants on postprandial triglyceride metabolism: impact of gender
Although apolipoprotein A-V (apoA-V) polymorphisms have been consistently associated with fasting triglyceride (TG) levels, their impact on postprandial lipemia remains relatively unknown. In this ...
- LIPIDS : - Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake
The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to ...
- LIPIDS & INTESTINAL FATTY ACID BINDING PROTEIN : - Intestinal fatty acid binding protein regulates mitochondrion β-oxidation and cholesterol uptake
The role of intestinal fatty acid binding protein (I-FABP) in lipid metabolism remains elusive. To address this issue, normal human intestinal epithelial cells (HIEC-6) were transfected with cDNA to ...
- LIPIDS & APOPTOSIS INDUCED RETICULOENDOPLASMIC ATYPICAL STRESS : - Apoptosis induced by t10,c12-conjugated linoleic acid is mediated by an atypical endoplasmic reticulum stress response
Conjugated linoleic acid (CLA) inhibits rat mammary carcinogenesis, in part by inducing apoptosis of preneoplastic and neoplastic mammary epithelial cells. The current study focused on the mechanism ...
- LIPIDS: Characterization and properties of preβ-HDL particles formed by ABCA1-mediated cellular lipid efflux to apoA-I
The contribution of ABCA1-mediated efflux of cellular phospholipid (PL) and cholesterol to human apolipoprotein A-I (apoA-I) to the formation of preβ1-HDL (or lipid-poor apoA-I) is not well ...
- LIPIDS : - Cholesterol supply and SREBPs modulate transcription of the Niemann-Pick C-1 gene in steroidogenic tissues
We tested whether sterol-regulatory element binding proteins (SREBPs) mediate sterol-regulated transactivation of the Niemann-Pick C-1 (NPC-1) gene. Loading granulosa cells with 22- or ...
- ¿METABOLIC SYNDROME? & HEPATIC STEATOSIS : - Mechanisms of hepatic steatosis in mice fed a lipogenic methionine choline-deficient diet
The methionine choline-deficient (MCD) diet results in liver injury similar to human nonalcoholic steatohepatitis (NASH). The aims of this study were to define mechanisms of MCD-induced steatosis in ...
- LIPIDS : - The Niemann-Pick C1 gene is downregulated by feedback inhibition of the SREBP pathway in human fibroblasts
The Niemann-Pick C1 (NPC1) protein regulates the transport of cholesterol from late endosomes/lysosomes to other compartments responsible for maintaining intracellular cholesterol homeostasis. The ...
- LIPIDS: - Congressional investigation into ENHANCE focusing on re-created expert panel minutes
Kenilworth and Whitehouse Station, NJ - The US House of Representatives Committee on Energy and Commerce has sent yet another letter to Merck & Co and Schering-Plough Corporation, reminding the ...
- LIPIDS :- Statins associated with increased progression of AMD, but caution is urged
A new study shows that the use of statins is associated with the progression of age-related macular degeneration (AMD), but the authors urge caution, saying that other causes may be the reason for ...
- CORONARY HEART DISEASE : -IDEAL Study : - Lowering triglycerides in stable statin-treated CHD patients does not provide benefit
A study presented this week casts some doubt on the clinical benefit of lowering triglyceride levels in statin-treated patients with stable coronary artery disease. This most recent analysis showed ...
- CARDIOLOGY: The influence of pravastatin and atorvastatin on markers of oxidative stress in hypercholesterolemic humans
Objectives: The aim of this study was to determine the effects of pravastatin and atorvastatin on markers of oxidative stress in plasma. Background: Hydroxymethylglutaryl coenzyme A reductase ...
- LIPIDS : Metabolism of apical vs. basolateral sn-2-monoacylglycerol and fatty acids in rodent small intestine
The metabolic fates of radiolabeled sn-2-monoolein (MG) and oleate (FA) in rat and mouse intestine, added in vivo to the apical (AP) surface in bile salt micelles, or to the basolateral (BL) surface ...
