Anales de Cuidados Críticos
Número 89, 15 de Junio de 2009
Contenido adicional
Noticias
- FARMACOLOGÍA EN EMERGENCIAS Y RCP: -La alternativa a la adrenalina en RCP aún no es una realidad
Uno de los retos de los intensivistas es disponer de vasopresores más selectivos que sean una alternativa a la adrenalina en la resucitación cardiopulmonar. Las investigaciones en este campo se ...
- CUIDADOS CRÍTICOS: -Los antioxidantes logran minimizar el efecto del estrés oxidativo en críticos
Es recomendable una administración diaria de nutrientes antioxidantes en pacientes con terapia de reemplazo renal y en los posquirúrgicos donde los fenómenos de isquemia/reperfusión en la cirugía ...
- CRITICAL CARE: -ACUTE SEPTIC LUNG INJURY & LOSARTAN EFFECTS: -Losartan prevents sepsis-induced acute lung injury and decreases activation of nuclear factor[kappa]B and mitogen-activated protein kinases.
Lack of specific and efficient therapy leads to the high mortality rate of acute lung injury (ALI) and acute respiratory distress syndrome (ARDS). Losartan is a potent pharmaceutical drug for ...
- CRITICAL CARE: - Elimination of C5a prevents intestinal mucosal damage and attenuates neutrophil infiltration in local and remote organs.
The complement C5a pathway has been shown to be an important mediator of inflammation and tissue injury. To further understand the role of C5a receptor (C5aR) pathway in ischemia/reperfusion (I/R) ...
- CRITICAL CARE: -Toll-Like receptor 4 regulates heme oxygenase-1 expression after hemorrhagic shock induced acute lung injury in mice: requirement of p38 mitogen-activated protein kinase activation.
Acute lung injury (ALI) leading to respiratory distress is a common sequela of shock or trauma. The toll-like receptors (TLRs) stand at the interface of innate immune activation in the settings of ...
- CRITICAL CARE: -Deferoxamine mimics the pattern of hypoxia-related injury at the microvasculature
Oxygen is essential for the maintenance of life, and when oxygen levels decline to critical levels, a program of complex mechanisms exists to i) sense hypoxia, ii) respond to minimize acute tissue ...
- CRITICAL CARE: SEPTIC SHOCK: -Coupled plasma filtration adsorption in experimental peritonitis-induced septic shock
The coupled plasma filtration adsorption (CPFA) was developed as an adsorptive hemopurification method aimed at nonselective removal of circulating soluble mediators potentially involved in the ...
- EXPERIMENTAL CRITICAL CARE IN ACUTE LUNG INJURY AND POSTINJURY HYPERINFLAMMATION: -Hypertonic saline attenuates TNF-[alpha]-Induced NF-[kappa]B activation in pulmonary epithelial cells.
Resuscitation with hypertonic saline (HTS) attenuates acute lung injury (ALI) and modulates postinjury hyperinflammation. TNF-[alpha]-stimulated pulmonary epithelium is a major contributor to ...
- CLINICAL CRITICAL CARE: -Estimated right ventricular systolic time intervals for the assessment of right ventricular function in acute respiratory distress syndrome.
Right ventricular (RV) systolic time intervals (STIs) have been shown to accurately reflect RV function in patients with acute respiratory distress syndrome (ARDS). The measurement of RVSTIs ...
- CLINICAL CRITICAL CARE: -Urinary liver-type fatty acid-binding protein in septic shock: effect of polymyxin b-immobilized fiber hemoperfusion
We aimed to determine retrospectively whether urinary liver-type fatty acid-binding protein (L-FABP) levels are altered in patients with septic shock or severe sepsis without shock and whether ...
- CRITICAL CARE: Endothelial nitric oxide synthase G894T (GLU298ASP) polymorphism is associated with hypotension in patients with e. coli bacteremia but not in bacteremia caused by a gram-positive organism.
Nitric oxide (NO) as a vasoactive substance is a crucial element in the pathogenesis of sepsis. Endothelial NO synthase (eNOS) is, in turn, a key regulator of vascular NO production. The eNOS gene ...
- CLINICAL VALUE: -CRITICAL CARE: -Validation of postinjury multiple organ failure scores.
Most multiple organ failure (MOF) scores were developed over a decade ago, but little has been done in terms of validation and to understand the differences between populations identified by each of ...
- MEDICINA RESPIRATORIA: -La mortalidad ligada al SDRA no ha disminuido en 15 años
Las cifras de mortalidad por síndrome de distrés respiratorio agudo (SDRA) son muy diferentes entre los pacientes incluidos en ensayos clínicos aleatorizados y las poblaciones reales, según una ...
- CUIDADOS CRÍTICOS: -Impact of noninvasive ventilation (NIV) trial for various types of acute respiratory failure in the emergency department; decreased mortality and use of the ICU
Background Trial of noninvasive ventilation (NIV) in the emergency department (ED) for heterogeneous acute respiratory failure (ARF) has been optional and its clinical benefit unclear.Methods We ...
- EMERGENTOLOGY: -No benefit of TNK in cardiac arrest: TROICA published
The first large-scale trial to investigate the addition of the thrombolytic tenecteplase (TNK) to standard cardiopulmonary resuscitation (CPR)—which showed no increase in survival in cardiac-arrest ...
