ADN: replicación, reparación y recombinación
DNA Interstrand Cross-links of the Novel Antitumor Trinuclear Platinum Complex BBR3464. CONFORMATION, RECOGNITION BY HIGH MOBILITY GROUP DOMAIN PROTEINS, AND NUCLEOTIDE EXCISION REPAIRDNA Interstrand Cross-links of the Novel Antitumor Trinuclear Platinum Complex BBR3464. CONFORMATION, RECOGNITION BY HIGH MOBILITY GROUP DOMAIN PROTEINS, AND NUCLEOTIDE EXCISION REPAIR
UV Stimulation of Nucleophosmin/B23 Expression Is an Immediate-early Gene Response Induced by Damaged DNAUV Stimulation of Nucleophosmin/B23 Expression Is an Immediate-early Gene Response Induced by Damaged DNA
Human DNA Polymerase Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA SynthesisHuman DNA Polymerase Functionally and Physically Interacts with Proliferating Cell Nuclear Antigen in Normal and Translesion DNA Synthesis
Involvement of Vertebrate Pol in Rad18-independent Postreplication Repair of UV DamageInvolvement of Vertebrate Pol in Rad18-independent Postreplication Repair of UV Damage
Regulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated PhosphorylationRegulation of Ionizing Radiation-induced Rad52 Nuclear Foci Formation by c-Abl-mediated Phosphorylation
2.4-Å Crystal Structure of the Asymmetric Platinum Complex {Pt(ammine)(cyclohexylamine)}2+ Bound to a Dodecamer DNA Duplex2.4-Å Crystal Structure of the Asymmetric Platinum Complex {Pt(ammine)(cyclohexylamine)}2+ Bound to a Dodecamer DNA Duplex
ARN: estructura, metabolismo y catálisis
Closely Related CC- and A-adding Enzymes Collaborate to Construct and Repair the 3'-Terminal CCA of tRNA in Synechocystis sp. and Deinococcus radioduransClosely Related CC- and A-adding Enzymes Collaborate to Construct and Repair the 3'-Terminal CCA of tRNA in Synechocystis sp. and Deinococcus radiodurans
The hU3-55K Protein Requires 15.5K Binding to the Box B/C Motif as Well as Flanking RNA Elements for Its Association with the U3 Small Nucleolar RNA in VitroThe hU3-55K Protein Requires 15.5K Binding to the Box B/C Motif as Well as Flanking RNA Elements for Its Association with the U3 Small Nucleolar RNA in Vitro
RNA Binding Properties of the AU-rich Element-binding Recombinant Nup475/TIS11/Tristetraprolin ProteinRNA Binding Properties of the AU-rich Element-binding Recombinant Nup475/TIS11/Tristetraprolin Protein
Bases moleculares de la célula y biología del desarrollo
Transitional Type 1 and 2 B Lymphocyte Subsets Are Differentially Responsive to Antigen Receptor SignalingTransitional Type 1 and 2 B Lymphocyte Subsets Are Differentially Responsive to Antigen Receptor Signaling
NAD(P)H Oxidase-derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production in Response to Angiotensin IINAD(P)H Oxidase-derived Hydrogen Peroxide Mediates Endothelial Nitric Oxide Production in Response to Angiotensin II
Autocrine Activation of the Hepatocyte Growth Factor Receptor/Met Tyrosine Kinase Induces Tumor Cell Motility by Regulating Pseudopodial ProtrusionAutocrine Activation of the Hepatocyte Growth Factor Receptor/Met Tyrosine Kinase Induces Tumor Cell Motility by Regulating Pseudopodial Protrusion
Effects of Overexpression of Membrane-bound Transferrin-like Protein (MTf) on Chondrogenic Differentiation in VitroEffects of Overexpression of Membrane-bound Transferrin-like Protein (MTf) on Chondrogenic Differentiation in Vitro
An Essential Function of Yeast Cyclin-dependent Kinase Cdc28 Maintains Chromosome StabilityAn Essential Function of Yeast Cyclin-dependent Kinase Cdc28 Maintains Chromosome Stability
Characterization of the Apoptosis Suppressor Protein P49 from the Spodoptera littoralis NucleopolyhedrovirusCharacterization of the Apoptosis Suppressor Protein P49 from the Spodoptera littoralis Nucleopolyhedrovirus
MBD3 and HDAC1, Two Components of the NuRD Complex, Are Localized at Aurora-A-positive Centrosomes in M PhaseMBD3 and HDAC1, Two Components of the NuRD Complex, Are Localized at Aurora-A-positive Centrosomes in M Phase
Oligomerization, F-actin Interaction, and Membrane Association of the Ubiquitous Mammalian Coronin 3 Are Mediated by Its Carboxyl TerminusOligomerization, F-actin Interaction, and Membrane Association of the Ubiquitous Mammalian Coronin 3 Are Mediated by Its Carboxyl Terminus
Nuclear Translocation of Plk1 Mediated by Its Bipartite Nuclear Localization SignalNuclear Translocation of Plk1 Mediated by Its Bipartite Nuclear Localization Signal
Mammalian Vestigial-like 2, a Cofactor of TEF-1 and MEF2 Transcription Factors That Promotes Skeletal Muscle DifferentiationMammalian Vestigial-like 2, a Cofactor of TEF-1 and MEF2 Transcription Factors That Promotes Skeletal Muscle Differentiation
The Novel Presenilin-1-associated Protein Is a Proapoptotic Mitochondrial ProteinThe Novel Presenilin-1-associated Protein Is a Proapoptotic Mitochondrial Protein
Interleukin-11 as a Stimulatory Factor for Bone Formation Prevents Bone Loss with Advancing Age in MiceInterleukin-11 as a Stimulatory Factor for Bone Formation Prevents Bone Loss with Advancing Age in Mice
Maize Tapetum Xylanase Is Synthesized as a Precursor, Processed and Activated by a Serine Protease, and Deposited on the PollenMaize Tapetum Xylanase Is Synthesized as a Precursor, Processed and Activated by a Serine Protease, and Deposited on the Pollen
Arrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK ActivationArrestin2 Is Critically Involved in CXCR4-mediated Chemotaxis, and This Is Mediated by Its Enhancement of p38 MAPK Activation
Neuritogenesis Induced by Thyroid Hormone-treated Astrocytes Is Mediated by Epidermal Growth Factor/Mitogen-activated Protein Kinase-Phosphatidylinositol 3-Kinase Pathways and Involves Modulation of Extracellular Matrix ProteinsNeuritogenesis Induced by Thyroid Hormone-treated Astrocytes Is Mediated by Epidermal Growth Factor/Mitogen-activated Protein Kinase-Phosphatidylinositol 3-Kinase Pathways and Involves Modulation of Extracellular Matrix Proteins
Bax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer CurvatureBax-type Apoptotic Proteins Porate Pure Lipid Bilayers through a Mechanism Sensitive to Intrinsic Monolayer Curvature
Phosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome SegregationPhosphorylation of the Mitotic Regulator Protein Hec1 by Nek2 Kinase Is Essential for Faithful Chromosome Segregation
Arsenic Trioxide Promotes Histone H3 Phosphoacetylation at the Chromatin of CASPASE-10 in Acute Promyelocytic Leukemia CellsArsenic Trioxide Promotes Histone H3 Phosphoacetylation at the Chromatin of CASPASE-10 in Acute Promyelocytic Leukemia Cells
Nerve Growth Factor (NGF) Down-regulates the Bcl-2 Homology 3 (BH3) Domain-only Protein Bim and Suppresses Its Proapoptotic Activity by PhosphorylationNerve Growth Factor (NGF) Down-regulates the Bcl-2 Homology 3 (BH3) Domain-only Protein Bim and Suppresses Its Proapoptotic Activity by Phosphorylation
Insulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling PathwayInsulin Receptor Substrate and p55 Orthologous Adaptor Proteins Function in the Caenorhabditis elegans daf-2/Insulin-like Signaling Pathway
The Drosophila DIAP1 Protein Is Required to Prevent Accumulation of a Continuously Generated, Processed Form of the Apical Caspase DRONCThe Drosophila DIAP1 Protein Is Required to Prevent Accumulation of a Continuously Generated, Processed Form of the Apical Caspase DRONC
Intraphagosomal Mycobacterium tuberculosis Acquires Iron from Both Extracellular Transferrin and Intracellular Iron Pools. IMPACT OF INTERFERON- AND HEMOCHROMATOSISIntraphagosomal Mycobacterium tuberculosis Acquires Iron from Both Extracellular Transferrin and Intracellular Iron Pools. IMPACT OF INTERFERON- AND HEMOCHROMATOSIS
Catálisis enzimática y regulación
Biochemical Evidence for an Editing Role of Thioesterase II in the Biosynthesis of the Polyketide PikromycinBiochemical Evidence for an Editing Role of Thioesterase II in the Biosynthesis of the Polyketide Pikromycin
The Calmodulin-binding Domain from a Plant Kinesin Functions as a Modular Domain in Conferring Ca2+-Calmodulin Regulation to Animal Plus- and Minus-end KinesinsThe Calmodulin-binding Domain from a Plant Kinesin Functions as a Modular Domain in Conferring Ca2+-Calmodulin Regulation to Animal Plus- and Minus-end Kinesins
The Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A AntimetaboliteThe Antibiotic Activity of N-Pentylpantothenamide Results from Its Conversion to Ethyldethia-Coenzyme A, a Coenzyme A Antimetabolite
The Metalloprotease Disintegrin ADAM8. PROCESSING BY AUTOCATALYSIS IS REQUIRED FOR PROTEOLYTIC ACTIVITY AND CELL ADHESIONThe Metalloprotease Disintegrin ADAM8. PROCESSING BY AUTOCATALYSIS IS REQUIRED FOR PROTEOLYTIC ACTIVITY AND CELL ADHESION
Purification, Characterization, Cloning, and Expression of a Novel Xyloglucan-specific Glycosidase, Oligoxyloglucan Reducing End-specific CellobiohydrolasePurification, Characterization, Cloning, and Expression of a Novel Xyloglucan-specific Glycosidase, Oligoxyloglucan Reducing End-specific Cellobiohydrolase
Checkpoint Kinase 2 (Chk2) Monomers or Dimers Phosphorylate Cdc25C after DNA Damage Regardless of Threonine 68 PhosphorylationCheckpoint Kinase 2 (Chk2) Monomers or Dimers Phosphorylate Cdc25C after DNA Damage Regardless of Threonine 68 Phosphorylation
Ferredoxin-NADP+ Reductase and Ferredoxin of the Protozoan Parasite Toxoplasma gondii Interact Productively in Vitro and in VivoFerredoxin-NADP+ Reductase and Ferredoxin of the Protozoan Parasite Toxoplasma gondii Interact Productively in Vitro and in Vivo
Autolytic Processing at Glu586-Ser587 within the Cysteine-rich Domain of Human Adamalysin 19/Disintegrin-Metalloproteinase 19 Is Necessary for Its Proteolytic ActivityAutolytic Processing at Glu586-Ser587 within the Cysteine-rich Domain of Human Adamalysin 19/Disintegrin-Metalloproteinase 19 Is Necessary for Its Proteolytic Activity
On the Binding Preference of Human Groups IIA and X Phospholipases A2 for Membranes with Anionic PhospholipidsOn the Binding Preference of Human Groups IIA and X Phospholipases A2 for Membranes with Anionic Phospholipids
Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2Interfacial Kinetic and Binding Properties of the Complete Set of Human and Mouse Groups I, II, V, X, and XII Secreted Phospholipases A2
Escherichia coli Glutamyl-tRNA Reductase. TRAPPING THE THIOESTER INTERMEDIATEEscherichia coli Glutamyl-tRNA Reductase. TRAPPING THE THIOESTER INTERMEDIATE
Modification of the Nucleotide Cofactor-binding Site of Cytochrome P-450 Reductase to Enhance Turnover with NADH in VivoModification of the Nucleotide Cofactor-binding Site of Cytochrome P-450 Reductase to Enhance Turnover with NADH in Vivo
The 99 and 170 Loop-modified Factor VIIa Mutants Show Enhanced Catalytic Activity without Tissue FactorThe 99 and 170 Loop-modified Factor VIIa Mutants Show Enhanced Catalytic Activity without Tissue Factor
Identification of Domain Required for Catalytic Activity of Auxilin in Supporting Clathrin Uncoating by Hsc70Identification of Domain Required for Catalytic Activity of Auxilin in Supporting Clathrin Uncoating by Hsc70
Activation of the Proton Transfer Pathway in Catalysis by Iron Superoxide DismutaseActivation of the Proton Transfer Pathway in Catalysis by Iron Superoxide Dismutase
Identification of a Potent and Orally Active Non-peptide C5a Receptor AntagonistIdentification of a Potent and Orally Active Non-peptide C5a Receptor Antagonist
Initial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm(/) Knockout Mouse. NOVEL MODEL SYSTEM FOR A SEVERELY COMPROMISED OXIDATIVE STRESS RESPONSEInitial Characterization of the Glutamate-Cysteine Ligase Modifier Subunit Gclm(/) Knockout Mouse. NOVEL MODEL SYSTEM FOR A SEVERELY COMPROMISED OXIDATIVE STRESS RESPONSE
The Nucleotide-binding Site of Human Sphingosine Kinase 1The Nucleotide-binding Site of Human Sphingosine Kinase 1
Enamelysin (Matrix Metalloproteinase 20)-deficient Mice Display an Amelogenesis Imperfecta PhenotypeEnamelysin (Matrix Metalloproteinase 20)-deficient Mice Display an Amelogenesis Imperfecta Phenotype
Degradation of Cellulose Substrates by Cellulosome Chimeras. SUBSTRATE TARGETING VERSUS PROXIMITY OF ENZYME COMPONENTSDegradation of Cellulose Substrates by Cellulosome Chimeras. SUBSTRATE TARGETING VERSUS PROXIMITY OF ENZYME COMPONENTS
The Activity of the Arabidopsis Bifunctional Lysine-ketoglutarate Reductase/Saccharopine Dehydrogenase Enzyme of Lysine Catabolism Is Regulated by Functional Interaction between Its Two Enzyme DomainsThe Activity of the Arabidopsis Bifunctional Lysine-ketoglutarate Reductase/Saccharopine Dehydrogenase Enzyme of Lysine Catabolism Is Regulated by Functional Interaction between Its Two Enzyme Domains
Kinetic Analysis of Arabidopsis Phospholipase D. SUBSTRATE PREFERENCE AND MECHANISM OF ACTIVATION BY Ca2+ AND PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATEKinetic Analysis of Arabidopsis Phospholipase D. SUBSTRATE PREFERENCE AND MECHANISM OF ACTIVATION BY Ca2+ AND PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE
Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine. EVIDENCE FOR A KETIMINE INTERMEDIATEApple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine. EVIDENCE FOR A KETIMINE INTERMEDIATE
The Role of Intersubunit Interactions for the Stabilization of the T State of Escherichia coli Aspartate TranscarbamoylaseThe Role of Intersubunit Interactions for the Stabilization of the T State of Escherichia coli Aspartate Transcarbamoylase
Genes: estructura y regulación
Differences in the Molecular Mechanisms Involved in the Transcriptional Activation of the CHOP and Asparagine Synthetase Genes in Response to Amino Acid Deprivation or Activation of the Unfolded Protein ResponseDifferences in the Molecular Mechanisms Involved in the Transcriptional Activation of the CHOP and Asparagine Synthetase Genes in Response to Amino Acid Deprivation or Activation of the Unfolded Protein Response
Multiple Mechanisms Contribute to the Activation of RNA Polymerase III Transcription in Cells Transformed by PapovavirusesMultiple Mechanisms Contribute to the Activation of RNA Polymerase III Transcription in Cells Transformed by Papovaviruses
Transcriptional Activation of the MUC2 Gene by p53Transcriptional Activation of the MUC2 Gene by p53
Cloning and Analysis of the Thrombopoietin-induced Megakaryocyte-specific Glycoprotein VI Promoter and Its Regulation by GATA-1, Fli-1, and Sp1Cloning and Analysis of the Thrombopoietin-induced Megakaryocyte-specific Glycoprotein VI Promoter and Its Regulation by GATA-1, Fli-1, and Sp1
Impaired Proliferation and Survival of Activated B Cells in Transgenic Mice That Express a Dominant-negative cAMP-response Element-binding Protein Transcription Factor in B CellsImpaired Proliferation and Survival of Activated B Cells in Transgenic Mice That Express a Dominant-negative cAMP-response Element-binding Protein Transcription Factor in B Cells
Involvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription ComplexInvolvement of Proteasome in the Dynamic Assembly of the Androgen Receptor Transcription Complex
Pem Homeobox Gene Regulatory Sequences That Direct Androgen-dependent Developmentally Regulated Gene Expression in Different Subregions of the EpididymisPem Homeobox Gene Regulatory Sequences That Direct Androgen-dependent Developmentally Regulated Gene Expression in Different Subregions of the Epididymis
Osteoclast Inhibitory Lectin, a Family of New Osteoclast InhibitorsOsteoclast Inhibitory Lectin, a Family of New Osteoclast Inhibitors
The Viral Oncogene Human Papillomavirus E7 Deregulates Transcriptional Silencing by Brm-related Gene 1 via Molecular InteractionsThe Viral Oncogene Human Papillomavirus E7 Deregulates Transcriptional Silencing by Brm-related Gene 1 via Molecular Interactions
Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1Characterization of a First Domain of Human High Glycine-Tyrosine and High Sulfur Keratin-associated Protein (KAP) Genes on Chromosome 21q22.1
Characterization of the Two Coactivator-interacting Surfaces of the Androgen Receptor and Their Relative Role in Transcriptional Control*Characterization of the Two Coactivator-interacting Surfaces of the Androgen Receptor and Their Relative Role in Transcriptional Control*
Modulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment TransactivationModulation of Induction Properties of Glucocorticoid Receptor-Agonist and -Antagonist Complexes by Coactivators Involves Binding to Receptors but Is Independent of Ability of Coactivators to Augment Transactivation
Transcriptional Regulation of Human Rev-erb Gene Expression by the Orphan Nuclear Receptor Retinoic Acid-related Orphan ReceptorTranscriptional Regulation of Human Rev-erb Gene Expression by the Orphan Nuclear Receptor Retinoic Acid-related Orphan Receptor
Salicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein- Binding via a Common Signaling PathwaySalicylate Suppresses Macrophage Nitric-oxide Synthase-2 and Cyclo-oxygenase-2 Expression by Inhibiting CCAAT/Enhancer-binding Protein- Binding via a Common Signaling Pathway
Cellular Response to an Antisense-mediated Shift of Bcl-x Pre-mRNA Splicing and Antineoplastic AgentsCellular Response to an Antisense-mediated Shift of Bcl-x Pre-mRNA Splicing and Antineoplastic Agents
Acetylation of Interferon Regulatory Factor-7 by p300/CREB-binding Protein (CBP)-associated Factor (PCAF) Impairs its DNA BindingAcetylation of Interferon Regulatory Factor-7 by p300/CREB-binding Protein (CBP)-associated Factor (PCAF) Impairs its DNA Binding
Transcription Factor Binding and Histone Modifications on the Integrated Proviral Promoter in Human T-cell Leukemia Virus-I-infected T-cellsTranscription Factor Binding and Histone Modifications on the Integrated Proviral Promoter in Human T-cell Leukemia Virus-I-infected T-cells
PAX6, Paired Domain Influences Sequence Recognition by the HomeodomainPAX6, Paired Domain Influences Sequence Recognition by the Homeodomain
Orientation-dependent Influence of an Intergenic Enhancer on the Promoter Activity of the Divergently Transcribed Mouse Shsp/B-crystallin and Mkbp/HspB2 GenesOrientation-dependent Influence of an Intergenic Enhancer on the Promoter Activity of the Divergently Transcribed Mouse Shsp/B-crystallin and Mkbp/HspB2 Genes
Genómica, proteómica y bioinformática
Comparative Genomics of Thiamin Biosynthesis in Procaryotes. NEW GENES AND REGULATORY MECHANISMSComparative Genomics of Thiamin Biosynthesis in Procaryotes. NEW GENES AND REGULATORY MECHANISMS
In Vivo Evidence for Interferon--mediated Homeostatic Mechanisms in Small Intestine of the NHE3 Na+/H+ Exchanger Knockout Model of Congenital DiarrheaIn Vivo Evidence for Interferon--mediated Homeostatic Mechanisms in Small Intestine of the NHE3 Na+/H+ Exchanger Knockout Model of Congenital Diarrhea
Cell-type and Donor-specific Transcriptional Responses to Interferon-. USE OF CUSTOMIZED GENE ARRAYSCell-type and Donor-specific Transcriptional Responses to Interferon-. USE OF CUSTOMIZED GENE ARRAYS
Glicobiología y matriz extracelular
Heparin and Heparan Sulfate Disaccharides Bind to the Exchanger Inhibitor Peptide Region of Na+/Ca2+ Exchanger and Reduce the Cytosolic Calcium of Smooth Muscle Cell Lines. REQUIREMENT OF C4-C5 UNSATURATION AND 1 4 GLYCOSIDIC LINKAGE FOR ACTIVITYHeparin and Heparan Sulfate Disaccharides Bind to the Exchanger Inhibitor Peptide Region of Na+/Ca2+ Exchanger and Reduce the Cytosolic Calcium of Smooth Muscle Cell Lines. REQUIREMENT OF C4-C5 UNSATURATION AND 1 4 GLYCOSIDIC LINKAGE FOR ACTIVITY
Isolation and Characterization of a Novel Rat Factor H-related Protein That Is Up-regulated in Glomeruli under Complement AttackIsolation and Characterization of a Novel Rat Factor H-related Protein That Is Up-regulated in Glomeruli under Complement Attack
Partial Structure of Glutamic Acid and Alanine-rich Protein, a Major Surface Glycoprotein of the Insect Stages of Trypanosoma congolensePartial Structure of Glutamic Acid and Alanine-rich Protein, a Major Surface Glycoprotein of the Insect Stages of Trypanosoma congolense
Biglycan Organizes Collagen VI into Hexagonal-like Networks Resembling Tissue StructuresBiglycan Organizes Collagen VI into Hexagonal-like Networks Resembling Tissue Structures
The Fine Structure of Caenorhabditis elegans N-GlycansThe Fine Structure of Caenorhabditis elegans N-Glycans
Cloning and Characterization of Two Extracellular Heparin-degrading Endosulfatases in Mice and HumansCloning and Characterization of Two Extracellular Heparin-degrading Endosulfatases in Mice and Humans
Location of N-Unsubstituted Glucosamine Residues in Heparan SulfateLocation of N-Unsubstituted Glucosamine Residues in Heparan Sulfate
Laminin-6 Is Activated by Proteolytic Processing and Regulates Cellular Adhesion and Migration Differently from Laminin-5Laminin-6 Is Activated by Proteolytic Processing and Regulates Cellular Adhesion and Migration Differently from Laminin-5
Regulation of Inositol Phospholipid Binding and Signaling through Syndecan-4Regulation of Inositol Phospholipid Binding and Signaling through Syndecan-4
The Hexapeptide Inhibitor of Gal1,3GalNAc-specific 2,3-Sialyltransferase as a Generic Inhibitor of SialyltransferasesThe Hexapeptide Inhibitor of Gal1,3GalNAc-specific 2,3-Sialyltransferase as a Generic Inhibitor of Sialyltransferases
Lípidos y lipoproteínas
Reduction of Atherosclerosis by the Peroxisome Proliferator-activated Receptor Agonist Fenofibrate in MiceReduction of Atherosclerosis by the Peroxisome Proliferator-activated Receptor Agonist Fenofibrate in Mice
Membrane Topology of the Acyl-Lipid Desaturase from Bacillus subtilisMembrane Topology of the Acyl-Lipid Desaturase from Bacillus subtilis
A Novel Host-Parasite Lipid Cross-talk. SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATIONA Novel Host-Parasite Lipid Cross-talk. SCHISTOSOMAL LYSO-PHOSPHATIDYLSERINE ACTIVATES TOLL-LIKE RECEPTOR 2 AND AFFECTS IMMUNE POLARIZATION
Transport of Cholesterol into Mitochondria Is Rate-limiting for Bile Acid Synthesis via the Alternative Pathway in Primary Rat HepatocytesTransport of Cholesterol into Mitochondria Is Rate-limiting for Bile Acid Synthesis via the Alternative Pathway in Primary Rat Hepatocytes
Effect of Charge Reversal Mutations on the Ligand- and Membrane-binding Properties of Liver Fatty Acid-binding ProteinEffect of Charge Reversal Mutations on the Ligand- and Membrane-binding Properties of Liver Fatty Acid-binding Protein
Induction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted A LevelsInduction of the Cholesterol Transporter ABCA1 in Central Nervous System Cells by Liver X Receptor Agonists Increases Secreted A Levels
Serum Lysophosphatidic Acid Is Produced through Diverse Phospholipase PathwaysSerum Lysophosphatidic Acid Is Produced through Diverse Phospholipase Pathways
Reduction of Blood Pressure, Plasma Cholesterol, and Atherosclerosis by Elevated Endothelial Nitric OxideReduction of Blood Pressure, Plasma Cholesterol, and Atherosclerosis by Elevated Endothelial Nitric Oxide
Increased Risk of Atherosclerosis by Elevated Plasma Levels of Phospholipid Transfer ProteinIncreased Risk of Atherosclerosis by Elevated Plasma Levels of Phospholipid Transfer Protein
Gangliosides Activate Trk Receptors by Inducing the Release of NeurotrophinsGangliosides Activate Trk Receptors by Inducing the Release of Neurotrophins
Membranas: transporte, estructura, función y biogénesis
Characterization of Drug Transport, ATP Hydrolysis, and Nucleotide Trapping by the Human ABCG2 Multidrug Transporter. MODULATION OF SUBSTRATE SPECIFICITY BY A POINT MUTATIONCharacterization of Drug Transport, ATP Hydrolysis, and Nucleotide Trapping by the Human ABCG2 Multidrug Transporter. MODULATION OF SUBSTRATE SPECIFICITY BY A POINT MUTATION
Modulation of the ERG K+ Current by the Tyrosine Phosphatase, SHP-1Modulation of the ERG K+ Current by the Tyrosine Phosphatase, SHP-1
A Role for the Middle C Terminus of G-protein-activated Inward Rectifier Potassium Channels in Regulating GatingA Role for the Middle C Terminus of G-protein-activated Inward Rectifier Potassium Channels in Regulating Gating
Vps51p Links the VFT Complex to the SNARE Tlg1pVps51p Links the VFT Complex to the SNARE Tlg1p
Molecular Cloning of a Fourth Member of the Potassium-dependent Sodium-Calcium Exchanger Gene Family, NCKX4Molecular Cloning of a Fourth Member of the Potassium-dependent Sodium-Calcium Exchanger Gene Family, NCKX4
Superactive SecY Variants That Fulfill the Essential Translocation Function with a Reduced Cellular QuantitySuperactive SecY Variants That Fulfill the Essential Translocation Function with a Reduced Cellular Quantity
A Novel Mutation (T65P) in the PAS Domain of the Human Potassium Channel HERG Results in the Long QT Syndrome by Trafficking DeficiencyA Novel Mutation (T65P) in the PAS Domain of the Human Potassium Channel HERG Results in the Long QT Syndrome by Trafficking Deficiency
Characterization of Isolated Acidocalcisomes from Toxoplasma gondii Tachyzoites Reveals a Novel Pool of Hydrolyzable PolyphosphateCharacterization of Isolated Acidocalcisomes from Toxoplasma gondii Tachyzoites Reveals a Novel Pool of Hydrolyzable Polyphosphate
Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway. IDENTIFICATION OF A NOVEL MEMBRANE TARGETING DOMAIN AND A ROLE FOR PALMITOYLATIONFlotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway. IDENTIFICATION OF A NOVEL MEMBRANE TARGETING DOMAIN AND A ROLE FOR PALMITOYLATION
Endocytosed Transferrin Receptors Recycle via Distinct Dynamin and Phosphatidylinositol 3-Kinase-dependent PathwaysEndocytosed Transferrin Receptors Recycle via Distinct Dynamin and Phosphatidylinositol 3-Kinase-dependent Pathways
A Novel Topology and Redox Regulation of the Rat Brain K+-dependent Na+/Ca2+ Exchanger, NCKX2A Novel Topology and Redox Regulation of the Rat Brain K+-dependent Na+/Ca2+ Exchanger, NCKX2
Interaction of Cofilin with Triose-phosphate Isomerase Contributes Glycolytic Fuel for Na,K-ATPase via Rho-mediated Signaling PathwayInteraction of Cofilin with Triose-phosphate Isomerase Contributes Glycolytic Fuel for Na,K-ATPase via Rho-mediated Signaling Pathway
Formation of Mutually Exclusive Rab11 Complexes with Members of the Family of Rab11-interacting Proteins Regulates Rab11 Endocytic Targeting and FunctionFormation of Mutually Exclusive Rab11 Complexes with Members of the Family of Rab11-interacting Proteins Regulates Rab11 Endocytic Targeting and Function
Rab11-FIP2, an Adaptor Protein Connecting Cellular Components Involved in Internalization and Recycling of Epidermal Growth Factor ReceptorsRab11-FIP2, an Adaptor Protein Connecting Cellular Components Involved in Internalization and Recycling of Epidermal Growth Factor Receptors
An ACTH- and ATP-regulated Background K+ Channel in Adrenocortical Cells Is TREK-1An ACTH- and ATP-regulated Background K+ Channel in Adrenocortical Cells Is TREK-1
The Intraacrosomal Calcium Pool Plays a Direct Role in Acrosomal ExocytosisThe Intraacrosomal Calcium Pool Plays a Direct Role in Acrosomal Exocytosis
Localization of the ATP/Phosphatidylinositol 4,5 Diphosphate-binding Site to a 39-Amino Acid Region of the Carboxyl Terminus of the ATP-regulated K+ Channel Kir1.1Localization of the ATP/Phosphatidylinositol 4,5 Diphosphate-binding Site to a 39-Amino Acid Region of the Carboxyl Terminus of the ATP-regulated K+ Channel Kir1.1
Sphingolipids Are Required for the Stable Membrane Association of Glycosylphosphatidylinositol-anchored Proteins in YeastSphingolipids Are Required for the Stable Membrane Association of Glycosylphosphatidylinositol-anchored Proteins in Yeast
A Lysine Substitute for K+. A460K MUTATION ELIMINATES K+ DEPENDENCE IN H+-PYROPHOSPHATASE OF CARBOXYDOTHERMUS HYDROGENOFORMANSA Lysine Substitute for K+. A460K MUTATION ELIMINATES K+ DEPENDENCE IN H+-PYROPHOSPHATASE OF CARBOXYDOTHERMUS HYDROGENOFORMANS
The Vesicle- and Target-SNARE Proteins That Mediate Glut4 Vesicle Fusion Are Localized in Detergent-insoluble Lipid Rafts Present on Distinct Intracellular MembranesThe Vesicle- and Target-SNARE Proteins That Mediate Glut4 Vesicle Fusion Are Localized in Detergent-insoluble Lipid Rafts Present on Distinct Intracellular Membranes
Analysis of the Antimalarial Drug Resistance Protein Pfcrt Expressed in YeastAnalysis of the Antimalarial Drug Resistance Protein Pfcrt Expressed in Yeast
Metabolismo y bioenergética
In Vivo Interactions between Gene Products Involved in the Final Stages of Molybdenum Cofactor Biosynthesis in Escherichia coliIn Vivo Interactions between Gene Products Involved in the Final Stages of Molybdenum Cofactor Biosynthesis in Escherichia coli
Tight Binding of Inhibitors to Bovine bc1 Complex Is Independent of the Rieske Protein Redox State. CONSEQUENCES FOR SEMIQUINONE STABILIZATION IN THE QUINOL OXIDATION SITETight Binding of Inhibitors to Bovine bc1 Complex Is Independent of the Rieske Protein Redox State. CONSEQUENCES FOR SEMIQUINONE STABILIZATION IN THE QUINOL OXIDATION SITE
Su e of the Yeast F1Fo-ATP Synthase Forms HomodimersSu e of the Yeast F1Fo-ATP Synthase Forms Homodimers
Pharmacogenetic Evidence That Cd36 Is a Key Determinant of the Metabolic Effects of PioglitazonePharmacogenetic Evidence That Cd36 Is a Key Determinant of the Metabolic Effects of Pioglitazone
A Pathogenic Cytochrome b Mutation Reveals New Interactions between Subunits of the Mitochondrial bc1 ComplexA Pathogenic Cytochrome b Mutation Reveals New Interactions between Subunits of the Mitochondrial bc1 Complex
Proteínas: estructura y función
The Aes Protein and the Monomeric -Galactosidase from Escherichia coli Form a Non-covalent Complex. IMPLICATIONS FOR THE REGULATION OF CARBOHYDRATE METABOLISMThe Aes Protein and the Monomeric -Galactosidase from Escherichia coli Form a Non-covalent Complex. IMPLICATIONS FOR THE REGULATION OF CARBOHYDRATE METABOLISM
Deletion Mutagenesis of Human Cystathionine -Synthase. IMPACT ON ACTIVITY, OLIGOMERIC STATUS, AND S-ADENOSYLMETHIONINE REGULATIONDeletion Mutagenesis of Human Cystathionine -Synthase. IMPACT ON ACTIVITY, OLIGOMERIC STATUS, AND S-ADENOSYLMETHIONINE REGULATION
Zinc Is Required for Assembly and Function of the Anti-trp RNA-binding Attenuation Protein, ATZinc Is Required for Assembly and Function of the Anti-trp RNA-binding Attenuation Protein, AT
Crystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) DomainCrystal Structure of the Cytoskeleton-associated Protein Glycine-rich (CAP-Gly) Domain
A Molecular Basis for Integrin M2 Ligand Binding PromiscuityA Molecular Basis for Integrin M2 Ligand Binding Promiscuity
Engineering the Refolding Pathway and the Quaternary Structure of Seminal Ribonuclease by Newly Introduced Disulfide BridgesEngineering the Refolding Pathway and the Quaternary Structure of Seminal Ribonuclease by Newly Introduced Disulfide Bridges
The Interactions of Cyanobacterial Cytochrome c6 and Cytochrome f, Characterized by NMRThe Interactions of Cyanobacterial Cytochrome c6 and Cytochrome f, Characterized by NMR
An Alanine-Zipper Structure Determined by Long Range Intermolecular InteractionsAn Alanine-Zipper Structure Determined by Long Range Intermolecular Interactions
Structure-based Design of p18INK4c Proteins with Increased Thermodynamic Stability and Cell Cycle Inhibitory ActivityStructure-based Design of p18INK4c Proteins with Increased Thermodynamic Stability and Cell Cycle Inhibitory Activity
A New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in -Conotoxin AuIB Reduces Structural Definition but Increases Biological ActivityA New Level of Conotoxin Diversity, a Non-native Disulfide Bond Connectivity in -Conotoxin AuIB Reduces Structural Definition but Increases Biological Activity
AGAP1, an Endosome-associated, Phosphoinositide-dependent ADP-ribosylation Factor GTPase-activating Protein That Affects Actin CytoskeletonAGAP1, an Endosome-associated, Phosphoinositide-dependent ADP-ribosylation Factor GTPase-activating Protein That Affects Actin Cytoskeleton
Disease-associated F198S Mutation Increases the Propensity of the Recombinant Prion Protein for Conformational Conversion to Scrapie-like FormDisease-associated F198S Mutation Increases the Propensity of the Recombinant Prion Protein for Conformational Conversion to Scrapie-like Form
A Truncated Plasminogen Activator Inhibitor-1 Protein Blocks the Availability of Heparin-binding Vascular Endothelial Growth Factor A IsoformsA Truncated Plasminogen Activator Inhibitor-1 Protein Blocks the Availability of Heparin-binding Vascular Endothelial Growth Factor A Isoforms
Structure/Function Relationships in the Minicollagen of Hydra NematocystsStructure/Function Relationships in the Minicollagen of Hydra Nematocysts
Dermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. ANTI-TRYPANOSOMA CRUZI ACTIVITY WITHOUT CYTOTOXICITY TO MAMMALIAN CELLSDermaseptins from Phyllomedusa oreades and Phyllomedusa distincta. ANTI-TRYPANOSOMA CRUZI ACTIVITY WITHOUT CYTOTOXICITY TO MAMMALIAN CELLS
Proteinaceous Infectious Behavior in Non-pathogenic Proteins Is Controlled by Molecular ChaperonesProteinaceous Infectious Behavior in Non-pathogenic Proteins Is Controlled by Molecular Chaperones
Cytotoxic Cell Granule-mediated Apoptosis. CHARACTERIZATION OF THE MACROMOLECULAR COMPLEX OF GRANZYME B WITH SERGLYCINCytotoxic Cell Granule-mediated Apoptosis. CHARACTERIZATION OF THE MACROMOLECULAR COMPLEX OF GRANZYME B WITH SERGLYCIN
Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Channels Lacking the N-terminal DomainAmino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Channels Lacking the N-terminal Domain
Publicaciones rápidas
Translocation of Small Preformed Vesicles Is Responsible for the Insulin Activation of Glucose Transport in Adipose Cells. EVIDENCE FROM THE IN VITRO RECONSTITUTION ASSAYTranslocation of Small Preformed Vesicles Is Responsible for the Insulin Activation of Glucose Transport in Adipose Cells. EVIDENCE FROM THE IN VITRO RECONSTITUTION ASSAY
Role of Pin1 in the Regulation of p53 Stability and p21 Transactivation, and Cell Cycle Checkpoints in Response to DNA DamageRole of Pin1 in the Regulation of p53 Stability and p21 Transactivation, and Cell Cycle Checkpoints in Response to DNA Damage
The p75 Neurotrophin Receptor Interacts with Multiple MAGE ProteinsThe p75 Neurotrophin Receptor Interacts with Multiple MAGE Proteins
Reflexiones
The Pentose Phosphate PathwayThe Pentose Phosphate Pathway
A Gold Mine of Fascinating Enzymes: Those Remarkable, Strictly Anaerobic Bacteria, Methanococcus vannielii and Clostridium sticklandiiA Gold Mine of Fascinating Enzymes: Those Remarkable, Strictly Anaerobic Bacteria, Methanococcus vannielii and Clostridium sticklandii
Síntesis proteica, post-translación, modificación y degradación
Human Adipose Tissue Cells Keep Tight Control on the Angiotensin II Levels in Their VicinityHuman Adipose Tissue Cells Keep Tight Control on the Angiotensin II Levels in Their Vicinity
Dopamine Biosynthesis Is Regulated by S-Glutathionylation. POTENTIAL MECHANISM OF TYROSINE HYDROXYLASE INHIBITION DURING OXIDATIVE STRESSDopamine Biosynthesis Is Regulated by S-Glutathionylation. POTENTIAL MECHANISM OF TYROSINE HYDROXYLASE INHIBITION DURING OXIDATIVE STRESS
Deficiencies in Pro-thyrotropin-releasing Hormone Processing and Abnormalities in Thermoregulation in Cpefat/fat MiceDeficiencies in Pro-thyrotropin-releasing Hormone Processing and Abnormalities in Thermoregulation in Cpefat/fat Mice
Utilization of a Novel Recombinant Myoglobin Fusion Protein Expression System to Characterize the Tissue Inhibitor of Metalloproteinase (TIMP)-4 and TIMP-2 C-terminal Domain and Tails by Mutagenesis. THE IMPORTANCE OF ACIDIC RESIDUES IN BINDING THE MMP-2Utilization of a Novel Recombinant Myoglobin Fusion Protein Expression System to Characterize the Tissue Inhibitor of Metalloproteinase (TIMP)-4 and TIMP-2 C-terminal Domain and Tails by Mutagenesis. THE IMPORTANCE OF ACIDIC RESIDUES IN BINDING THE MMP-2
Phosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP). STIMULATION OF TRANSCRIPTIONAL REGULATION BY MITOGEN-ACTIVATED PROTEIN KINASEPhosphorylation of Transcriptional Coactivator Peroxisome Proliferator-activated Receptor (PPAR)-binding Protein (PBP). STIMULATION OF TRANSCRIPTIONAL REGULATION BY MITOGEN-ACTIVATED PROTEIN KINASE
Identification in Human Atherosclerotic Lesions of GA-pyridine, a Novel Structure Derived from Glycolaldehyde-modified ProteinsIdentification in Human Atherosclerotic Lesions of GA-pyridine, a Novel Structure Derived from Glycolaldehyde-modified Proteins
Characterization of Cytoplasmic -Synuclein Aggregates. FIBRIL FORMATION IS TIGHTLY LINKED TO THE INCLUSION-FORMING PROCESS IN CELLSCharacterization of Cytoplasmic -Synuclein Aggregates. FIBRIL FORMATION IS TIGHTLY LINKED TO THE INCLUSION-FORMING PROCESS IN CELLS
Golgi Fragmentation Occurs in the Cells with Prefibrillar -Synuclein Aggregates and Precedes the Formation of Fibrillar InclusionGolgi Fragmentation Occurs in the Cells with Prefibrillar -Synuclein Aggregates and Precedes the Formation of Fibrillar Inclusion
Phosphorylated -Synuclein Is Ubiquitinated in -Synucleinopathy LesionsPhosphorylated -Synuclein Is Ubiquitinated in -Synucleinopathy Lesions
Isoprenylation of RhoB Is Necessary for Its Degradation. A NOVEL DETERMINANT IN THE COMPLEX REGULATION OF RhoB EXPRESSION BY THE MEVALONATE PATHWAYIsoprenylation of RhoB Is Necessary for Its Degradation. A NOVEL DETERMINANT IN THE COMPLEX REGULATION OF RhoB EXPRESSION BY THE MEVALONATE PATHWAY
A Lack of SUMO Conjugation Affects cNLS-dependent Nuclear Protein Import in YeastA Lack of SUMO Conjugation Affects cNLS-dependent Nuclear Protein Import in Yeast
Nuclear Localization of Peptidylarginine Deiminase V and Histone Deimination in GranulocytesNuclear Localization of Peptidylarginine Deiminase V and Histone Deimination in Granulocytes
Characterization of Drosophila Carboxypeptidase DCharacterization of Drosophila Carboxypeptidase D
MdmX Is a RING Finger Ubiquitin Ligase Capable of Synergistically Enhancing Mdm2 UbiquitinationMdmX Is a RING Finger Ubiquitin Ligase Capable of Synergistically Enhancing Mdm2 Ubiquitination
Transducción de señales y mecanismos
Death-associated Protein 4 Binds MST1 and Augments MST1-induced ApoptosisDeath-associated Protein 4 Binds MST1 and Augments MST1-induced Apoptosis
Protein Phosphatase-1 Binding to Scd5p Is Important for Regulation of Actin Organization and Endocytosis in YeastProtein Phosphatase-1 Binding to Scd5p Is Important for Regulation of Actin Organization and Endocytosis in Yeast
Kainate-binding Proteins Are Rendered Functional Ion Channels upon Transplantation of Two Short Pore-flanking Domains from a Kainate ReceptorKainate-binding Proteins Are Rendered Functional Ion Channels upon Transplantation of Two Short Pore-flanking Domains from a Kainate Receptor
NRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial PathwayNRAGE, a p75 Neurotrophin Receptor-interacting Protein, Induces Caspase Activation and Cell Death through a JNK-dependent Mitochondrial Pathway
Cell Condition-dependent Regulation of ERK5 by cAMPCell Condition-dependent Regulation of ERK5 by cAMP
Serine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor B Kinase ComplexSerine Phosphorylation of Insulin Receptor Substrate 1 by Inhibitor B Kinase Complex
Multimerization of the Protein-tyrosine Phosphatase (PTP)-like Insulin-dependent Diabetes Mellitus Autoantigens IA-2 and IA-2 with Receptor PTPs (RPTPs). INHIBITION OF RPTP ENZYMATIC ACTIVITYMultimerization of the Protein-tyrosine Phosphatase (PTP)-like Insulin-dependent Diabetes Mellitus Autoantigens IA-2 and IA-2 with Receptor PTPs (RPTPs). INHIBITION OF RPTP ENZYMATIC ACTIVITY
cAMP-dependent Protein Kinase and Ca2+ Influx through L-type Voltage-gated Calcium Channels Mediate Raf-independent Activation of Extracellular Regulated Kinase in Response to Glucagon-like Peptide-1 in Pancreatic -CellscAMP-dependent Protein Kinase and Ca2+ Influx through L-type Voltage-gated Calcium Channels Mediate Raf-independent Activation of Extracellular Regulated Kinase in Response to Glucagon-like Peptide-1 in Pancreatic -Cells
Cyclic Strain Activates Redox-sensitive Proline-rich Tyrosine Kinase 2 (PYK2) in Endothelial CellsCyclic Strain Activates Redox-sensitive Proline-rich Tyrosine Kinase 2 (PYK2) in Endothelial Cells
Epidermal Growth Factor-induced Depletion of the Intracellular Ca2+ Store Fails to Activate Capacitative Ca2+ Entry in a Human Salivary Cell LineEpidermal Growth Factor-induced Depletion of the Intracellular Ca2+ Store Fails to Activate Capacitative Ca2+ Entry in a Human Salivary Cell Line
Ca2+-dependent Protein Kinase-A Modulation of the Plasma Membrane Ca2+-ATPase in Parotid Acinar CellsCa2+-dependent Protein Kinase-A Modulation of the Plasma Membrane Ca2+-ATPase in Parotid Acinar Cells
Carboxyl-terminal Sequences Critical for Inositol 1,4,5-Trisphosphate Receptor Subunit AssemblyCarboxyl-terminal Sequences Critical for Inositol 1,4,5-Trisphosphate Receptor Subunit Assembly
Phosphorylation of the Platelet-derived Growth Factor Receptor- and Epidermal Growth Factor Receptor by G Protein-coupled Receptor Kinase-2. MECHANISMS FOR SELECTIVITY OF DESENSITIZATIONPhosphorylation of the Platelet-derived Growth Factor Receptor- and Epidermal Growth Factor Receptor by G Protein-coupled Receptor Kinase-2. MECHANISMS FOR SELECTIVITY OF DESENSITIZATION
Contribution of the Kir3.1 Subunit to the Muscarinic-gated Atrial Potassium Channel IKAChContribution of the Kir3.1 Subunit to the Muscarinic-gated Atrial Potassium Channel IKACh
Selective Association of TRPC Channel Subunits in Rat Brain SynaptosomesSelective Association of TRPC Channel Subunits in Rat Brain Synaptosomes
Regulator of G Protein Signaling Z1 (RGSZ1) Interacts with Gi Subunits and Regulates Gi-mediated Cell SignalingRegulator of G Protein Signaling Z1 (RGSZ1) Interacts with Gi Subunits and Regulates Gi-mediated Cell Signaling
Activation of SAPK/JNK Signaling by Protein Kinase C in Response to DNA DamageActivation of SAPK/JNK Signaling by Protein Kinase C in Response to DNA Damage
Rac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer CellsRac1-MKK3-p38-MAPKAPK2 Pathway Promotes Urokinase Plasminogen Activator mRNA Stability in Invasive Breast Cancer Cells
Induction of Hypoxia-inducible Factor-1 by Transcriptional and Translational MechanismsInduction of Hypoxia-inducible Factor-1 by Transcriptional and Translational Mechanisms
Growth Hormone-induced Diacylglycerol and Ceramide Formation via Gi3 and G in GH4 Pituitary Cells. POTENTIATION BY DOPAMINE-D2 RECEPTOR ACTIVATIONGrowth Hormone-induced Diacylglycerol and Ceramide Formation via Gi3 and G in GH4 Pituitary Cells. POTENTIATION BY DOPAMINE-D2 RECEPTOR ACTIVATION
Regulation of Calcium/Calmodulin-dependent Protein Kinase II Docking to N-Methyl-D-aspartate Receptors by Calcium/Calmodulin and -ActininRegulation of Calcium/Calmodulin-dependent Protein Kinase II Docking to N-Methyl-D-aspartate Receptors by Calcium/Calmodulin and -Actinin
Regulation of WNK1 by an Autoinhibitory Domain and AutophosphorylationRegulation of WNK1 by an Autoinhibitory Domain and Autophosphorylation
Interfering with Nitric Oxide Measurements. 4,5-DIAMINOFLUORESCEIN REACTS WITH DEHYDROASCORBIC ACID AND ASCORBIC ACIDInterfering with Nitric Oxide Measurements. 4,5-DIAMINOFLUORESCEIN REACTS WITH DEHYDROASCORBIC ACID AND ASCORBIC ACID
Mutations in the Estrogen Receptor DNA-binding Domain Discriminate between the Classical Mechanism of Action and Cross-talk with Stat5b and Activating Protein 1 (AP-1)Mutations in the Estrogen Receptor DNA-binding Domain Discriminate between the Classical Mechanism of Action and Cross-talk with Stat5b and Activating Protein 1 (AP-1)
Insulin Signal Transduction Pathways and Insulin-induced Gene ExpressionInsulin Signal Transduction Pathways and Insulin-induced Gene Expression
Ferric Ions Are Essential for the Biological Activity of the Hormone Glycine-extended GastrinFerric Ions Are Essential for the Biological Activity of the Hormone Glycine-extended Gastrin
Requirement of Nuclear Factor of Activated T-cells in Calcineurin-mediated Cardiomyocyte HypertrophyRequirement of Nuclear Factor of Activated T-cells in Calcineurin-mediated Cardiomyocyte Hypertrophy
Protein Kinase A Negatively Modulates the Nuclear Accumulation of NF-ATc1 by Priming for Subsequent Phosphorylation by Glycogen Synthase Kinase-3Protein Kinase A Negatively Modulates the Nuclear Accumulation of NF-ATc1 by Priming for Subsequent Phosphorylation by Glycogen Synthase Kinase-3
P2Y Purinoceptors Are Responsible for Oscillatory Fluid Flow-induced Intracellular Calcium Mobilization in Osteoblastic CellsP2Y Purinoceptors Are Responsible for Oscillatory Fluid Flow-induced Intracellular Calcium Mobilization in Osteoblastic Cells
The Phox Homology (PX) Domain-dependent, 3-Phosphoinositide-mediated Association of Sorting Nexin-1 with an Early Sorting Endosomal Compartment Is Required for Its Ability to Regulate Epidermal Growth Factor Receptor DegradationThe Phox Homology (PX) Domain-dependent, 3-Phosphoinositide-mediated Association of Sorting Nexin-1 with an Early Sorting Endosomal Compartment Is Required for Its Ability to Regulate Epidermal Growth Factor Receptor Degradation
Gastrin Stimulates Cyclooxygenase-2 Expression in Intestinal Epithelial Cells through Multiple Signaling Pathways. EVIDENCE FOR INVOLVEMENT OF ERK5 KINASE AND TRANSACTIVATION OF THE EPIDERMAL GROWTH FACTOR RECEPTORGastrin Stimulates Cyclooxygenase-2 Expression in Intestinal Epithelial Cells through Multiple Signaling Pathways. EVIDENCE FOR INVOLVEMENT OF ERK5 KINASE AND TRANSACTIVATION OF THE EPIDERMAL GROWTH FACTOR RECEPTOR
Activation of the Rb/E2F1 Pathway by the Nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated Neuronal ApoptosisActivation of the Rb/E2F1 Pathway by the Nonproliferative p38 MAPK during Fas (APO1/CD95)-mediated Neuronal Apoptosis
Analyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ HomeostasisAnalyzing the Role of the Putative Inositol 1,3,4,5-Tetrakisphosphate Receptor GAP1IP4BP in Intracellular Ca2+ Homeostasis
Cellular Conditioning and Activation of -Catenin Signaling by the FPB Prostanoid ReceptorCellular Conditioning and Activation of -Catenin Signaling by the FPB Prostanoid Receptor
Mapping the Protein Phosphatase-2B Anchoring Site on AKAP79. BINDING AND INHIBITION OF PHOSPHATASE ACTIVITY ARE MEDIATED BY RESIDUES 315-360Mapping the Protein Phosphatase-2B Anchoring Site on AKAP79. BINDING AND INHIBITION OF PHOSPHATASE ACTIVITY ARE MEDIATED BY RESIDUES 315-360
Genetic Selection of Peptide Inhibitors of Human Immunodeficiency Virus Type 1 VprGenetic Selection of Peptide Inhibitors of Human Immunodeficiency Virus Type 1 Vpr
Parathyroid Hormone Stimulates Receptor Activator of NFB Ligand and Inhibits Osteoprotegerin Expression via Protein Kinase A Activation of cAMP-response Element-binding ProteinParathyroid Hormone Stimulates Receptor Activator of NFB Ligand and Inhibits Osteoprotegerin Expression via Protein Kinase A Activation of cAMP-response Element-binding Protein
Zinc-dependent Interaction between Dishevelled and the Drosophila Wnt Antagonist Naked CuticleZinc-dependent Interaction between Dishevelled and the Drosophila Wnt Antagonist Naked Cuticle
Activation of an Unfolded Protein Response during Differentiation of Antibody-secreting B CellsActivation of an Unfolded Protein Response during Differentiation of Antibody-secreting B Cells
Stimulus-specific Requirements for MAP3 Kinases in Activating the JNK PathwayStimulus-specific Requirements for MAP3 Kinases in Activating the JNK Pathway
Fibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein KinaseFibroblast Growth Factor Homologous Factors and the Islet Brain-2 Scaffold Protein Regulate Activation of a Stress-activated Protein Kinase
Inhibition of Apoptosis by Amphiregulin via an Insulin-like Growth Factor-1 Receptor-dependent Pathway in Non-small Cell Lung Cancer Cell LinesInhibition of Apoptosis by Amphiregulin via an Insulin-like Growth Factor-1 Receptor-dependent Pathway in Non-small Cell Lung Cancer Cell Lines
Protein Kinase C Associates with the Interleukin-6 Receptor Subunit Glycoprotein (gp) 130 via Stat3 and Enhances Stat3-gp130 InteractionProtein Kinase C Associates with the Interleukin-6 Receptor Subunit Glycoprotein (gp) 130 via Stat3 and Enhances Stat3-gp130 Interaction
Suramin Interacts with the Calmodulin Binding Site on the Ryanodine Receptor, RYR1Suramin Interacts with the Calmodulin Binding Site on the Ryanodine Receptor, RYR1
Characterization of Signaling Pathways Activated by the Interleukin 1 (IL-1) Receptor Homologue T1/ST2. A ROLE FOR JUN N-TERMINAL KINASE IN IL-4 INDUCTIONCharacterization of Signaling Pathways Activated by the Interleukin 1 (IL-1) Receptor Homologue T1/ST2. A ROLE FOR JUN N-TERMINAL KINASE IN IL-4 INDUCTION
Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase RegulationLiver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation
Modulation of T Cell Cytokine Production by Interferon Regulatory Factor-4Modulation of T Cell Cytokine Production by Interferon Regulatory Factor-4
Branched Chain Fatty Acids Induce Nitric Oxide-dependent Apoptosis in Vascular Smooth Muscle CellsBranched Chain Fatty Acids Induce Nitric Oxide-dependent Apoptosis in Vascular Smooth Muscle Cells
Erf4p and Erf2p Form an Endoplasmic Reticulum-associated Complex Involved in the Plasma Membrane Localization of Yeast Ras ProteinsErf4p and Erf2p Form an Endoplasmic Reticulum-associated Complex Involved in the Plasma Membrane Localization of Yeast Ras Proteins
Association of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription ElongationAssociation of the Histone Methyltransferase Set2 with RNA Polymerase II Plays a Role in Transcription Elongation
The Transcriptional Activator Mirk/Dyrk1B Is Sequestered by p38/ MAP KinaseThe Transcriptional Activator Mirk/Dyrk1B Is Sequestered by p38/ MAP Kinase
Evidence for a Causal Role of CD38 Expression in Granulocytic Differentiation of Human HL-60 CellsEvidence for a Causal Role of CD38 Expression in Granulocytic Differentiation of Human HL-60 Cells
K252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERKK252a and CEP1347 Are Neuroprotective Compounds That Inhibit Mixed-lineage Kinase-3 and Induce Activation of Akt and ERK
CXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their SurvivalCXCR4 Is a Major Chemokine Receptor on Glioma Cells and Mediates Their Survival
Corepressor SMRT Functions as a Coactivator for Thyroid Hormone Receptor T3R from a Negative Hormone Response ElementCorepressor SMRT Functions as a Coactivator for Thyroid Hormone Receptor T3R from a Negative Hormone Response Element
Ceramide Signaling in Fenretinide-induced Endothelial Cell ApoptosisCeramide Signaling in Fenretinide-induced Endothelial Cell Apoptosis
Regulation of Intracellular pH Mediates Bax Activation in HeLa Cells Treated with Staurosporine or Tumor Necrosis Factor-Regulation of Intracellular pH Mediates Bax Activation in HeLa Cells Treated with Staurosporine or Tumor Necrosis Factor-
ERK1/2 Antagonizes Glycogen Synthase Kinase-3-induced Apoptosis in Cortical NeuronsERK1/2 Antagonizes Glycogen Synthase Kinase-3-induced Apoptosis in Cortical Neurons
The Expression of the PDZ Protein MALS-1/Velis Is Regulated by Calcium and Calcineurin in Cerebellar Granule CellsThe Expression of the PDZ Protein MALS-1/Velis Is Regulated by Calcium and Calcineurin in Cerebellar Granule Cells
A Novel Transmembrane Ser/Thr Kinase Complexes with Protein Phosphatase-1 and Inhibitor-2A Novel Transmembrane Ser/Thr Kinase Complexes with Protein Phosphatase-1 and Inhibitor-2
Cholesterol Depletion from the Plasma Membrane Triggers Ligand-independent Activation of the Epidermal Growth Factor ReceptorCholesterol Depletion from the Plasma Membrane Triggers Ligand-independent Activation of the Epidermal Growth Factor Receptor
The Anti-apoptotic Function of Hsp70 in the Interferon-inducible Double-stranded RNA-dependent Protein Kinase-mediated Death Signaling Pathway Requires the Fanconi Anemia Protein, FANCCThe Anti-apoptotic Function of Hsp70 in the Interferon-inducible Double-stranded RNA-dependent Protein Kinase-mediated Death Signaling Pathway Requires the Fanconi Anemia Protein, FANCC
Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic -Cells (INS-1)Protein Kinase B/Akt Prevents Fatty Acid-induced Apoptosis in Pancreatic -Cells (INS-1)
Calcium Sensing Receptor Activation by a Calcimimetic Suggests a Link between Cooperativity and Intracellular Calcium OscillationsCalcium Sensing Receptor Activation by a Calcimimetic Suggests a Link between Cooperativity and Intracellular Calcium Oscillations
Role of Dynamic Interactions in Effective Signal Transfer for G Stimulation of Phospholipase C-2Role of Dynamic Interactions in Effective Signal Transfer for G Stimulation of Phospholipase C-2
Engineering Competitive Magnesium Binding into the First EF-hand of Skeletal Troponin CEngineering Competitive Magnesium Binding into the First EF-hand of Skeletal Troponin C
Glucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHPGlucocorticoid Signaling Is Perturbed by the Atypical Orphan Receptor and Corepressor SHP
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