ADN: replicación, reparación y recombinación
Strand Transfer Occurs in Retroviruses by a Pause-initiated Two-step MechanismStrand Transfer Occurs in Retroviruses by a Pause-initiated Two-step Mechanism
On the Specificity of Interaction between the Saccharomyces cerevisiae Clamp Loader Replication Factor C and Primed DNA Templates during DNA ReplicationOn the Specificity of Interaction between the Saccharomyces cerevisiae Clamp Loader Replication Factor C and Primed DNA Templates during DNA Replication
Human Ku70/80 Associates Physically with Telomerase through Interaction with hTERTHuman Ku70/80 Associates Physically with Telomerase through Interaction with hTERT
Efficiency of Correct Nucleotide Insertion Governs DNA Polymerase FidelityEfficiency of Correct Nucleotide Insertion Governs DNA Polymerase Fidelity
Bases moleculares de la célula y biología del desarrollo
The Cleavage of the Urokinase Receptor Regulates Its Multiple FunctionsThe Cleavage of the Urokinase Receptor Regulates Its Multiple Functions
Kinetic Regulation of 3 Integrin Tyrosine PhosphorylationKinetic Regulation of 3 Integrin Tyrosine Phosphorylation
Heteromultimerization Modulates P2X Receptor Functions through Participating Extracellular and C-terminal SubdomainsHeteromultimerization Modulates P2X Receptor Functions through Participating Extracellular and C-terminal Subdomains
Complex Nuclear Localization Signals in the Matrix Protein of Vesicular Stomatitis VirusComplex Nuclear Localization Signals in the Matrix Protein of Vesicular Stomatitis Virus
DYRK3 Activation, Engagement of Protein Kinase A/cAMP Response Element-binding Protein, and Modulation of Progenitor Cell SurvivalDYRK3 Activation, Engagement of Protein Kinase A/cAMP Response Element-binding Protein, and Modulation of Progenitor Cell Survival
Two Nonconsensus Sites in the Epstein-Barr Virus Oncoprotein EBNA3A Cooperate to Bind the Co-repressor Carboxyl-terminal-binding Protein (CtBP)Two Nonconsensus Sites in the Epstein-Barr Virus Oncoprotein EBNA3A Cooperate to Bind the Co-repressor Carboxyl-terminal-binding Protein (CtBP)
RNA Interference of Signal Peptide-binding Protein SRP54 Elicits Deleterious Effects and Protein Sorting Defects in TrypanosomesRNA Interference of Signal Peptide-binding Protein SRP54 Elicits Deleterious Effects and Protein Sorting Defects in Trypanosomes
Identification of the Structure and Origin of Thioacidolysis Marker Compounds for Cinnamyl Alcohol Dehydrogenase Deficiency in AngiospermsIdentification of the Structure and Origin of Thioacidolysis Marker Compounds for Cinnamyl Alcohol Dehydrogenase Deficiency in Angiosperms
Interleukins 19, 20, and 24 Signal through Two Distinct Receptor Complexes. DIFFERENCES IN RECEPTOR-LIGAND INTERACTIONS MEDIATE UNIQUE BIOLOGICAL FUNCTIONSInterleukins 19, 20, and 24 Signal through Two Distinct Receptor Complexes. DIFFERENCES IN RECEPTOR-LIGAND INTERACTIONS MEDIATE UNIQUE BIOLOGICAL FUNCTIONS
Function of Region I and II Adhesive Motifs of Plasmodium falciparum Circumsporozoite Protein in Sporozoite Motility and InfectivityFunction of Region I and II Adhesive Motifs of Plasmodium falciparum Circumsporozoite Protein in Sporozoite Motility and Infectivity
Identification and Characterization of a Soluble Cadherin-7 Isoform Produced by Alternative SplicingIdentification and Characterization of a Soluble Cadherin-7 Isoform Produced by Alternative Splicing
The Rho GTPase Effector Protein, mDia, Inhibits the DNA Binding Ability of the Transcription Factor Pax6 and Changes the Pattern of Neurite Extension in Cerebellar Granule Cells through Its Binding to Pax6The Rho GTPase Effector Protein, mDia, Inhibits the DNA Binding Ability of the Transcription Factor Pax6 and Changes the Pattern of Neurite Extension in Cerebellar Granule Cells through Its Binding to Pax6
Characterization of a Novel Mammalian Groucho Isoform and Its Role in Transcriptional RegulationCharacterization of a Novel Mammalian Groucho Isoform and Its Role in Transcriptional Regulation
Catálisis enzimática y regulación
Identification of a Magnesium-dependent NAD(P)(H)-binding Domain in the Nicotinoprotein Methanol Dehydrogenase from Bacillus methanolicusIdentification of a Magnesium-dependent NAD(P)(H)-binding Domain in the Nicotinoprotein Methanol Dehydrogenase from Bacillus methanolicus
Acyl-Enzyme Complexes between Tissue-type Plasminogen Activator and Neuroserpin are Short-lived in VitroAcyl-Enzyme Complexes between Tissue-type Plasminogen Activator and Neuroserpin are Short-lived in Vitro
Analysis of O-Acetyl-ADP-ribose as a Target for Nudix ADP-ribose HydrolasesAnalysis of O-Acetyl-ADP-ribose as a Target for Nudix ADP-ribose Hydrolases
Transfer of Cholesterol between Phospholipid Vesicles Mediated by the Steroidogenic Acute Regulatory Protein (StAR)Transfer of Cholesterol between Phospholipid Vesicles Mediated by the Steroidogenic Acute Regulatory Protein (StAR)
Nitric Oxide (NO) Pretreatment Increases Cytokine-induced NO Production in Cultured Rat Hepatocytes by Suppressing GTP Cyclohydrolase I Feedback Inhibitory Protein Level and Promoting Inducible NO Synthase DimerizationNitric Oxide (NO) Pretreatment Increases Cytokine-induced NO Production in Cultured Rat Hepatocytes by Suppressing GTP Cyclohydrolase I Feedback Inhibitory Protein Level and Promoting Inducible NO Synthase Dimerization
The Extreme C Terminus of Rat Liver Carnitine Palmitoyltransferase I Is Not Involved in Malonyl-CoA Sensitivity but in Initial Protein FoldingThe Extreme C Terminus of Rat Liver Carnitine Palmitoyltransferase I Is Not Involved in Malonyl-CoA Sensitivity but in Initial Protein Folding
Cell Surface Targeting of Pregnancy-associated Plasma Protein A Proteolytic Activity. REVERSIBLE ADHESION IS MEDIATED BY TWO NEIGHBORING SHORT CONSENSUS REPEATSCell Surface Targeting of Pregnancy-associated Plasma Protein A Proteolytic Activity. REVERSIBLE ADHESION IS MEDIATED BY TWO NEIGHBORING SHORT CONSENSUS REPEATS
Conserved Residues in the Putative Catalytic Triad of Human Bile Acid Coenzyme A:Amino Acid N-AcyltransferaseConserved Residues in the Putative Catalytic Triad of Human Bile Acid Coenzyme A:Amino Acid N-Acyltransferase
Protease Nexin 1 Is a Potent Urinary Plasminogen Activator Inhibitor in the Presence of Collagen Type IVProtease Nexin 1 Is a Potent Urinary Plasminogen Activator Inhibitor in the Presence of Collagen Type IV
Stabilization of the R Allosteric Structure of Escherichia coli Aspartate Transcarbamoylase by Disulfide Bond FormationStabilization of the R Allosteric Structure of Escherichia coli Aspartate Transcarbamoylase by Disulfide Bond Formation
Nudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator Ribose 1,5-BisphosphateNudix Hydrolases That Degrade Dinucleoside and Diphosphoinositol Polyphosphates Also Have 5-Phosphoribosyl 1-Pyrophosphate (PRPP) Pyrophosphatase Activity That Generates the Glycolytic Activator Ribose 1,5-Bisphosphate
Phosphorylation of Isolated Human Phosphodiesterase-5 Regulatory Domain Induces an Apparent Conformational Change and Increases cGMP Binding AffinityPhosphorylation of Isolated Human Phosphodiesterase-5 Regulatory Domain Induces an Apparent Conformational Change and Increases cGMP Binding Affinity
Unexpected Advanced Generation Cephalosporinase Activity of the M69F Variant of SHV -LactamaseUnexpected Advanced Generation Cephalosporinase Activity of the M69F Variant of SHV -Lactamase
Unusual Proteolytic Activation of Pro-hepatocyte Growth Factor by Plasma Kallikrein and Coagulation Factor XIaUnusual Proteolytic Activation of Pro-hepatocyte Growth Factor by Plasma Kallikrein and Coagulation Factor XIa
Genes: estructura y regulación
Identification of Three NFAT Binding Motifs in the 5'-Upstream Region of the Human CD3 Gene That Differentially Bind NFATc1, NFATc2, and NF-B p50Identification of Three NFAT Binding Motifs in the 5'-Upstream Region of the Human CD3 Gene That Differentially Bind NFATc1, NFATc2, and NF-B p50
Molecular Basis for the Loss of CD28 Expression in Senescent T CellsMolecular Basis for the Loss of CD28 Expression in Senescent T Cells
Specific Activation of Human Interleukin-5 Depends on de Novo Synthesis of an AP-1 ComplexSpecific Activation of Human Interleukin-5 Depends on de Novo Synthesis of an AP-1 Complex
Identification of Functional Hypoxia Response Elements in the Promoter Region of the DEC1 and DEC2 GenesIdentification of Functional Hypoxia Response Elements in the Promoter Region of the DEC1 and DEC2 Genes
A Key Role for the 1 Helix of Human RAP74 in the Initiation and Elongation of RNA ChainsA Key Role for the 1 Helix of Human RAP74 in the Initiation and Elongation of RNA Chains
Novel Target Sequences for Pax-6 in the Brain-specific Activating Regions of the Rat Aldolase C GeneNovel Target Sequences for Pax-6 in the Brain-specific Activating Regions of the Rat Aldolase C Gene
Promoter Analysis and Regulatory Characteristics of vvhBA Encoding Cytolytic Hemolysin of Vibrio vulnificusPromoter Analysis and Regulatory Characteristics of vvhBA Encoding Cytolytic Hemolysin of Vibrio vulnificus
Characterization of the Extended Myb-like DNA-binding Domain of Trithorax Group Protein ZesteCharacterization of the Extended Myb-like DNA-binding Domain of Trithorax Group Protein Zeste
Promoter Use by 38 (rpoS) RNA Polymerase. AMINO ACID CLUSTERS FOR DNA BINDING AND ISOMERIZATIONPromoter Use by 38 (rpoS) RNA Polymerase. AMINO ACID CLUSTERS FOR DNA BINDING AND ISOMERIZATION
Serine Repeat Antigen (SERA5) Is Predominantly Expressed among the SERA Multigene Family of Plasmodium falciparum, and the Acquired Antibody Titers Correlate with Serum Inhibition of the Parasite GrowthSerine Repeat Antigen (SERA5) Is Predominantly Expressed among the SERA Multigene Family of Plasmodium falciparum, and the Acquired Antibody Titers Correlate with Serum Inhibition of the Parasite Growth
Cloning and Expression Analysis of Two Mucin-like Genes Encoding Microfilarial Sheath Surface Proteins of the Parasitic Nematodes Brugia and LitomosoidesCloning and Expression Analysis of Two Mucin-like Genes Encoding Microfilarial Sheath Surface Proteins of the Parasitic Nematodes Brugia and Litomosoides
T Cell-specific Expression of the Murine CD3 PromoterT Cell-specific Expression of the Murine CD3 Promoter
Genómica, proteómica y bioinformática
A Novel Sterol 14-Demethylase/Ferredoxin Fusion Protein (MCCYP51FX) from Methylococcus capsulatus Represents a New Class of the Cytochrome P450 SuperfamilyA Novel Sterol 14-Demethylase/Ferredoxin Fusion Protein (MCCYP51FX) from Methylococcus capsulatus Represents a New Class of the Cytochrome P450 Superfamily
A Single Amino Acid Difference between Human and Monkey Interleukin (IL)-1 Dictates Effective Binding to Soluble Type II IL-1 ReceptorA Single Amino Acid Difference between Human and Monkey Interleukin (IL)-1 Dictates Effective Binding to Soluble Type II IL-1 Receptor
FOXO Proteins Regulate Tumor Necrosis Factor-related Apoptosis Inducing Ligand Expression. IMPLICATIONS FOR PTEN MUTATION IN PROSTATE CANCERFOXO Proteins Regulate Tumor Necrosis Factor-related Apoptosis Inducing Ligand Expression. IMPLICATIONS FOR PTEN MUTATION IN PROSTATE CANCER
Glicobiología y matriz extracelular
The Lectin Domain of UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 1 Is Involved in O-Glycosylation of a Polypeptide with Multiple Acceptor SitesThe Lectin Domain of UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase 1 Is Involved in O-Glycosylation of a Polypeptide with Multiple Acceptor Sites
Ganglioside Induces Caveolin-1 Redistribution and Interaction with the Epidermal Growth Factor ReceptorGanglioside Induces Caveolin-1 Redistribution and Interaction with the Epidermal Growth Factor Receptor
Localization of the Carbohydrate Recognition Sites of the Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor to Domains 3 and 9 of the Extracytoplasmic RegionLocalization of the Carbohydrate Recognition Sites of the Insulin-like Growth Factor II/Mannose 6-Phosphate Receptor to Domains 3 and 9 of the Extracytoplasmic Region
Deficiency in Matrix Metalloproteinase Gelatinase B (MMP-9) Protects against Retinal Ganglion Cell Death after Optic Nerve LigationDeficiency in Matrix Metalloproteinase Gelatinase B (MMP-9) Protects against Retinal Ganglion Cell Death after Optic Nerve Ligation
A Potential Endogenous Ligand of Annexin IV in the Exocrine Pancreas. CARBOHYDRATE STRUCTURE OF GP-2, A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED GLYCOPROTEIN OF ZYMOGEN GRANULEA Potential Endogenous Ligand of Annexin IV in the Exocrine Pancreas. CARBOHYDRATE STRUCTURE OF GP-2, A GLYCOSYLPHOSPHATIDYLINOSITOL-ANCHORED GLYCOPROTEIN OF ZYMOGEN GRANULE
Distribution of PG-M/Versican Variants in Human Tissues and de Novo Expression of Isoform V3 upon Endothelial Cell Activation, Migration, and Neoangiogenesis in VitroDistribution of PG-M/Versican Variants in Human Tissues and de Novo Expression of Isoform V3 upon Endothelial Cell Activation, Migration, and Neoangiogenesis in Vitro
Studies on the Function of Oligosaccharyl Transferase Subunits. Stt3p IS DIRECTLY INVOLVED IN THE GLYCOSYLATION PROCESSStudies on the Function of Oligosaccharyl Transferase Subunits. Stt3p IS DIRECTLY INVOLVED IN THE GLYCOSYLATION PROCESS
Molecular Cloning and Characterization of a Novel UDP-Gal:GalNAc Peptide 1,3-Galactosyltransferase (C1Gal-T2), an Enzyme Synthesizing a Core 1 Structure of O-GlycanMolecular Cloning and Characterization of a Novel UDP-Gal:GalNAc Peptide 1,3-Galactosyltransferase (C1Gal-T2), an Enzyme Synthesizing a Core 1 Structure of O-Glycan
The (1,3)-Fucosyltransferase Fuc-TIV, but Not Fuc-TVII, Generates Sialyl Lewis X-like Epitopes Preferentially on GlycolipidsThe (1,3)-Fucosyltransferase Fuc-TIV, but Not Fuc-TVII, Generates Sialyl Lewis X-like Epitopes Preferentially on Glycolipids
Lípidos y lipoproteínas
Lipoprotein(a) Enhances Advanced Atherosclerosis and Vascular Calcification in WHHL Transgenic Rabbits Expressing Human Apolipoprotein(a)Lipoprotein(a) Enhances Advanced Atherosclerosis and Vascular Calcification in WHHL Transgenic Rabbits Expressing Human Apolipoprotein(a)
Role of Charge Properties of Bacterial Envelope in Bactericidal Action of Human Group IIA Phospholipase A2 against Staphylococcus aureusRole of Charge Properties of Bacterial Envelope in Bactericidal Action of Human Group IIA Phospholipase A2 against Staphylococcus aureus
Defining the Importance of Phosphatidylserine Synthase 2 in MiceDefining the Importance of Phosphatidylserine Synthase 2 in Mice
The Saccharomyces cerevisiae LSB6 Gene Encodes Phosphatidylinositol 4-Kinase ActivityThe Saccharomyces cerevisiae LSB6 Gene Encodes Phosphatidylinositol 4-Kinase Activity
An Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell ActivationAn Essential Role for Albumin in the Interaction of Endotoxin with Lipopolysaccharide-binding Protein and sCD14 and Resultant Cell Activation
Membranas: transporte, estructura, función y biogénesis
Biochemical Characterization of CopA, the Escherichia coli Cu(I)-translocating P-type ATPaseBiochemical Characterization of CopA, the Escherichia coli Cu(I)-translocating P-type ATPase
Alphavirus 6K Proteins Form Ion ChannelsAlphavirus 6K Proteins Form Ion Channels
Identification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton. POTENTIAL ROLE IN THROMBIN-MEDIATED PLATELET ADHESIONIdentification of Dp71 Isoforms in the Platelet Membrane Cytoskeleton. POTENTIAL ROLE IN THROMBIN-MEDIATED PLATELET ADHESION
Equilibrative and Concentrative Nucleoside Transporters Mediate Influx of Extracellular Cyclic ADP-Ribose into 3T3 Murine FibroblastsEquilibrative and Concentrative Nucleoside Transporters Mediate Influx of Extracellular Cyclic ADP-Ribose into 3T3 Murine Fibroblasts
Heat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial CellsHeat-evoked Activation of TRPV4 Channels in a HEK293 Cell Expression System and in Native Mouse Aorta Endothelial Cells
CaT1 Contributes to the Stores-operated Calcium Current in Jurkat T-lymphocytesCaT1 Contributes to the Stores-operated Calcium Current in Jurkat T-lymphocytes
Arf1 Dissociates from the Clathrin Adaptor GGA Prior to Being Inactivated by Arf GTPase-activating ProteinsArf1 Dissociates from the Clathrin Adaptor GGA Prior to Being Inactivated by Arf GTPase-activating Proteins
Hypoxia and 2-Agonists Regulate Cell Surface Expression of the Epithelial Sodium Channel in Native Alveolar Epithelial CellsHypoxia and 2-Agonists Regulate Cell Surface Expression of the Epithelial Sodium Channel in Native Alveolar Epithelial Cells
Structural Requirements for Interactions between Leucine-sorting Signals and Clathrin-associated Adaptor Protein Complex AP3Structural Requirements for Interactions between Leucine-sorting Signals and Clathrin-associated Adaptor Protein Complex AP3
Intercellular Transfer of the Cellular Prion ProteinIntercellular Transfer of the Cellular Prion Protein
In Vitro Fusion of Plant Golgi Membranes Can Be Influenced by Divalent CationsIn Vitro Fusion of Plant Golgi Membranes Can Be Influenced by Divalent Cations
A Novel Anterograde Trafficking Signal Present in the N-terminal Extracellular Domain of Ionotropic Glutamate ReceptorsA Novel Anterograde Trafficking Signal Present in the N-terminal Extracellular Domain of Ionotropic Glutamate Receptors
Non-canonical Transit Peptide for Import into the ChloroplastNon-canonical Transit Peptide for Import into the Chloroplast
Interaction with GM130 during HERG Ion Channel Trafficking. DISRUPTION BY TYPE 2 CONGENITAL LONG QT SYNDROME MUTATIONSInteraction with GM130 during HERG Ion Channel Trafficking. DISRUPTION BY TYPE 2 CONGENITAL LONG QT SYNDROME MUTATIONS
The Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery PathwaysThe Ccz1-Mon1 Protein Complex Is Required for the Late Step of Multiple Vacuole Delivery Pathways
Metabolismo y bioenergética
Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side. STUDIES USING TARGETED ANTIOXIDANTSSuperoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side. STUDIES USING TARGETED ANTIOXIDANTS
Uncoupling Protein-3 (UCP3) mRNA Expression in Reconstituted Human Muscle after Myoblast Transplantation in RAG2//c/C5 Immunodeficient MiceUncoupling Protein-3 (UCP3) mRNA Expression in Reconstituted Human Muscle after Myoblast Transplantation in RAG2//c/C5 Immunodeficient Mice
Proteínas: estructura y función
Characterization of T7 RNA Polymerase Transcription Complexes Assembled on Nucleic Acid ScaffoldsCharacterization of T7 RNA Polymerase Transcription Complexes Assembled on Nucleic Acid Scaffolds
The N Terminus of ClpB from Thermus thermophilus Is Not Essential for the Chaperone ActivityThe N Terminus of ClpB from Thermus thermophilus Is Not Essential for the Chaperone Activity
The N Terminus of the MUC2 Mucin Forms Trimers That Are Held Together within a Trypsin-resistant Core FragmentThe N Terminus of the MUC2 Mucin Forms Trimers That Are Held Together within a Trypsin-resistant Core Fragment
X-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic ActivityX-ray Structure of Two Crystalline Forms of a Streptomycete Ribonuclease with Cytotoxic Activity
Molecular Characterization of a Novel Fibronectin-binding Protein of Streptococcus pyogenes Strains Isolated from Toxic Shock-like Syndrome PatientsMolecular Characterization of a Novel Fibronectin-binding Protein of Streptococcus pyogenes Strains Isolated from Toxic Shock-like Syndrome Patients
A Single-domain Cyclophilin from Leishmania donovani Reactivates Soluble Aggregates of Adenosine Kinase by Isomerase-independent Chaperone FunctionA Single-domain Cyclophilin from Leishmania donovani Reactivates Soluble Aggregates of Adenosine Kinase by Isomerase-independent Chaperone Function
Crystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin BiosynthesisCrystal Structure of OxyB, a Cytochrome P450 Implicated in an Oxidative Phenol Coupling Reaction during Vancomycin Biosynthesis
Characterization of the Structure and Dynamics of a Near-native Equilibrium Intermediate in the Unfolding Pathway of an All -Barrel ProteinCharacterization of the Structure and Dynamics of a Near-native Equilibrium Intermediate in the Unfolding Pathway of an All -Barrel Protein
Oxidation-induced Misfolding and Aggregation of Superoxide Dismutase and Its Implications for Amyotrophic Lateral SclerosisOxidation-induced Misfolding and Aggregation of Superoxide Dismutase and Its Implications for Amyotrophic Lateral Sclerosis
Function and Solution Structure of Huwentoxin-IV, a Potent Neuronal Tetrodotoxin (TTX)-sensitive Sodium Channel Antagonist from Chinese Bird Spider Selenocosmia huwenaFunction and Solution Structure of Huwentoxin-IV, a Potent Neuronal Tetrodotoxin (TTX)-sensitive Sodium Channel Antagonist from Chinese Bird Spider Selenocosmia huwena
Protein-RNA Interactions and Virus Stability as Probed by the Dynamics of Tryptophan Side ChainsProtein-RNA Interactions and Virus Stability as Probed by the Dynamics of Tryptophan Side Chains
Phosphorylation-induced Conformational Changes in a Mitogen-activated Protein Kinase Substrate. IMPLICATIONS FOR TYROSINE HYDROXYLASE ACTIVATIONPhosphorylation-induced Conformational Changes in a Mitogen-activated Protein Kinase Substrate. IMPLICATIONS FOR TYROSINE HYDROXYLASE ACTIVATION
Oligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITYOligosaccharide and Sucrose Complexes of Amylosucrase. STRUCTURAL IMPLICATIONS FOR THE POLYMERASE ACTIVITY
HLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural AlterationsHLA-B27 Subtypes Differentially Associated with Disease Exhibit Subtle Structural Alterations
Parkin Accumulation in Aggresomes Due to Proteasome ImpairmentParkin Accumulation in Aggresomes Due to Proteasome Impairment
Zinc Mediates Assembly of the T1 Domain of the Voltage-gated K Channel 4.2Zinc Mediates Assembly of the T1 Domain of the Voltage-gated K Channel 4.2
Structure-Activity Relationships of Linear and Cyclic Peptides Containing the NGR Tumor-homing MotifStructure-Activity Relationships of Linear and Cyclic Peptides Containing the NGR Tumor-homing Motif
Sulfate Respiration in Desulfovibrio vulgaris Hildenborough. STRUCTURE OF THE 16-HEME CYTOCHROME c HmcA AT 2.5-Å RESOLUTION AND A VIEW OF ITS ROLE IN TRANSMEMBRANE ELECTRON TRANSFERSulfate Respiration in Desulfovibrio vulgaris Hildenborough. STRUCTURE OF THE 16-HEME CYTOCHROME c HmcA AT 2.5-Å RESOLUTION AND A VIEW OF ITS ROLE IN TRANSMEMBRANE ELECTRON TRANSFER
Publicaciones rápidas
Silencing of Midgut Aminopeptidase N of Spodoptera litura by Double-stranded RNA Establishes Its Role as Bacillus thuringiensis Toxin ReceptorSilencing of Midgut Aminopeptidase N of Spodoptera litura by Double-stranded RNA Establishes Its Role as Bacillus thuringiensis Toxin Receptor
Maspin Inhibits Cell Migration in the Absence of Protease Inhibitory ActivityMaspin Inhibits Cell Migration in the Absence of Protease Inhibitory Activity
Revisiones
Proteomics and Models for Enzyme CooperativityProteomics and Models for Enzyme Cooperativity
Síntesis proteica, post-translación, modificación y degradación
Characterization of a Unique Glycosylated Anchor Endopeptidase That Cleaves the LPXTG Sequence Motif of Cell Surface Proteins of Gram-positive BacteriaCharacterization of a Unique Glycosylated Anchor Endopeptidase That Cleaves the LPXTG Sequence Motif of Cell Surface Proteins of Gram-positive Bacteria
The Position of Cysteine Relative to the Transmembrane Domain Is Critical for Palmitoylation of H1, the Major Subunit of the Human Asialoglycoprotein ReceptorThe Position of Cysteine Relative to the Transmembrane Domain Is Critical for Palmitoylation of H1, the Major Subunit of the Human Asialoglycoprotein Receptor
Cleavage of p21waf1 by Proteinase-3, a Myeloid-specific Serine Protease, Potentiates Cell ProliferationCleavage of p21waf1 by Proteinase-3, a Myeloid-specific Serine Protease, Potentiates Cell Proliferation
Functional ATPase Activity of p97/Valosin-containing Protein (VCP) Is Required for the Quality Control of Endoplasmic Reticulum in Neuronally Differentiated Mammalian PC12 CellsFunctional ATPase Activity of p97/Valosin-containing Protein (VCP) Is Required for the Quality Control of Endoplasmic Reticulum in Neuronally Differentiated Mammalian PC12 Cells
NHE1 Regulates the Stratum Corneum Permeability Barrier Homeostasis. MICROENVIRONMENT ACIDIFICATION ASSESSED WITH FLUORESCENCE LIFETIME IMAGINGNHE1 Regulates the Stratum Corneum Permeability Barrier Homeostasis. MICROENVIRONMENT ACIDIFICATION ASSESSED WITH FLUORESCENCE LIFETIME IMAGING
BAP, a Mammalian BiP-associated Protein, Is a Nucleotide Exchange Factor That Regulates the ATPase Activity of BiPBAP, a Mammalian BiP-associated Protein, Is a Nucleotide Exchange Factor That Regulates the ATPase Activity of BiP
Identification of a Multifunctional Binding Site on Ubc9p Required for Smt3p ConjugationIdentification of a Multifunctional Binding Site on Ubc9p Required for Smt3p Conjugation
Mitochondrial DNA Instability Mutants of the Bifunctional Protein Ilv5p Have Altered Organization in Mitochondria and Are Targeted for Degradation by Hsp78 and the Pim1p ProteaseMitochondrial DNA Instability Mutants of the Bifunctional Protein Ilv5p Have Altered Organization in Mitochondria and Are Targeted for Degradation by Hsp78 and the Pim1p Protease
Transducción de señales y mecanismos
Two Different Signals Regulate Repression and Induction of Gene Expression by GlucoseTwo Different Signals Regulate Repression and Induction of Gene Expression by Glucose
A Death-associated Protein Kinase (DAPK)-interacting Protein, DIP-1, Is an E3 Ubiquitin Ligase That Promotes Tumor Necrosis Factor-induced Apoptosis and Regulates the Cellular Levels of DAPKA Death-associated Protein Kinase (DAPK)-interacting Protein, DIP-1, Is an E3 Ubiquitin Ligase That Promotes Tumor Necrosis Factor-induced Apoptosis and Regulates the Cellular Levels of DAPK
An Ephrin Mimetic Peptide That Selectively Targets the EphA2 ReceptorAn Ephrin Mimetic Peptide That Selectively Targets the EphA2 Receptor
CD27 and CD40 Inhibit p53-independent Mitochondrial Pathways in Apoptosis of B Cells Induced by B Cell Receptor LigationCD27 and CD40 Inhibit p53-independent Mitochondrial Pathways in Apoptosis of B Cells Induced by B Cell Receptor Ligation
Dual G1 and G2 Phase Inhibition by a Novel, Selective Cdc25 Inhibitor 7-Chloro-6-(2-morpholin-4-ylethylamino)- quinoline-5,8-dioneDual G1 and G2 Phase Inhibition by a Novel, Selective Cdc25 Inhibitor 7-Chloro-6-(2-morpholin-4-ylethylamino)- quinoline-5,8-dione
Ca2+-stimulated Ca2+ Oscillations Produced by the Ca2+-sensing Receptor Require Negative Feedback by Protein Kinase CCa2+-stimulated Ca2+ Oscillations Produced by the Ca2+-sensing Receptor Require Negative Feedback by Protein Kinase C
Novel Role for Low Molecular Weight Plasma Thiols in Nitric Oxide-mediated Control of Platelet FunctionNovel Role for Low Molecular Weight Plasma Thiols in Nitric Oxide-mediated Control of Platelet Function
Regulation of Glycoprotein Ib-IX-von Willebrand Factor Interaction by cAMP-dependent Protein Kinase-mediated Phosphorylation at Ser 166 of Glycoprotein IbRegulation of Glycoprotein Ib-IX-von Willebrand Factor Interaction by cAMP-dependent Protein Kinase-mediated Phosphorylation at Ser 166 of Glycoprotein Ib
Cell Death Inhibiting RNA (CDIR) Derived from a 3'-Untranslated Region Binds AUF1 and Heat Shock Protein 27Cell Death Inhibiting RNA (CDIR) Derived from a 3'-Untranslated Region Binds AUF1 and Heat Shock Protein 27
An N-terminal Region of Caenorhabditis elegans RGS Proteins EGL-10 and EAT-16 Directs Inhibition of Go Versus Gq SignalingAn N-terminal Region of Caenorhabditis elegans RGS Proteins EGL-10 and EAT-16 Directs Inhibition of Go Versus Gq Signaling
Molecular Examination of the Transmembrane Requirements of the Platelet-derived Growth Factor Receptor for a Productive Interaction with the Bovine Papillomavirus E5 OncoproteinMolecular Examination of the Transmembrane Requirements of the Platelet-derived Growth Factor Receptor for a Productive Interaction with the Bovine Papillomavirus E5 Oncoprotein
Differential Gene Regulation by Specific Gain-of-function JNK1 Proteins Expressed in Swiss 3T3 FibroblastsDifferential Gene Regulation by Specific Gain-of-function JNK1 Proteins Expressed in Swiss 3T3 Fibroblasts
Requirement of Mitogen-activated Protein Kinase Kinase 3 (MKK3) for Activation of p38 and p38 MAPK Isoforms by TGF-1 in Murine Mesangial CellsRequirement of Mitogen-activated Protein Kinase Kinase 3 (MKK3) for Activation of p38 and p38 MAPK Isoforms by TGF-1 in Murine Mesangial Cells
Intra- and Intermolecular Interactions between Intracellular Domains of Receptor Protein-tyrosine PhosphatasesIntra- and Intermolecular Interactions between Intracellular Domains of Receptor Protein-tyrosine Phosphatases
Phosphatidylinositol 5-Phosphate Biosynthesis Is Linked to PIKfyve and Is Involved in Osmotic Response Pathway in Mammalian CellsPhosphatidylinositol 5-Phosphate Biosynthesis Is Linked to PIKfyve and Is Involved in Osmotic Response Pathway in Mammalian Cells
Binding of the Concave Surface of the Sds22 Superhelix to the 4/5/6-Triangle of Protein Phosphatase-1Binding of the Concave Surface of the Sds22 Superhelix to the 4/5/6-Triangle of Protein Phosphatase-1
U0126 and PD98059, Specific Inhibitors of MEK, Accelerate Differentiation of RAW264.7 Cells into Osteoclast-like CellsU0126 and PD98059, Specific Inhibitors of MEK, Accelerate Differentiation of RAW264.7 Cells into Osteoclast-like Cells
A CD36-initiated Signaling Cascade Mediates Inflammatory Effects of -AmyloidA CD36-initiated Signaling Cascade Mediates Inflammatory Effects of -Amyloid
Comparison of the Functional Insulin Binding Epitopes of the A and B Isoforms of the Insulin ReceptorComparison of the Functional Insulin Binding Epitopes of the A and B Isoforms of the Insulin Receptor
Inhibition of p38 MAPK by Glucocorticoids via Induction of MAPK Phosphatase-1 Enhances Nontypeable Haemophilus influenzae-induced Expression of Toll-like Receptor 2Inhibition of p38 MAPK by Glucocorticoids via Induction of MAPK Phosphatase-1 Enhances Nontypeable Haemophilus influenzae-induced Expression of Toll-like Receptor 2
Stimulation of the Raf/MEK/ERK Cascade Is Necessary and Sufficient for Activation and Thr-160 Phosphorylation of a Nuclear-targeted CDK2Stimulation of the Raf/MEK/ERK Cascade Is Necessary and Sufficient for Activation and Thr-160 Phosphorylation of a Nuclear-targeted CDK2
Interaction of p38 and Sp1 in a Mechanical Force-induced, 1 Integrin-mediated Transcriptional Circuit That Regulates the Actin-binding Protein Filamin-AInteraction of p38 and Sp1 in a Mechanical Force-induced, 1 Integrin-mediated Transcriptional Circuit That Regulates the Actin-binding Protein Filamin-A
SHP-2 Is a Dual-specificity Phosphatase Involved in Stat1 Dephosphorylation at Both Tyrosine and Serine Residues in NucleiSHP-2 Is a Dual-specificity Phosphatase Involved in Stat1 Dephosphorylation at Both Tyrosine and Serine Residues in Nuclei
Coordinated Signaling through Both G12/13 and Gi Pathways Is Sufficient to Activate GPIIb/IIIa in Human PlateletsCoordinated Signaling through Both G12/13 and Gi Pathways Is Sufficient to Activate GPIIb/IIIa in Human Platelets
Insulin-like Growth Factor I Triggers Nuclear Accumulation of Cyclin D1 in MCF-7S Breast Cancer CellsInsulin-like Growth Factor I Triggers Nuclear Accumulation of Cyclin D1 in MCF-7S Breast Cancer Cells
Metal Ion-mediated Agonism and Agonist Enhancement in Melanocortin MC1 and MC4 ReceptorsMetal Ion-mediated Agonism and Agonist Enhancement in Melanocortin MC1 and MC4 Receptors
Structural Requirements for Mutational Lutropin/Choriogonadotropin Receptor ActivationStructural Requirements for Mutational Lutropin/Choriogonadotropin Receptor Activation
Subtype-specific Expression of Group III Metabotropic Glutamate Receptors and Ca2+ Channels in Single Nerve TerminalsSubtype-specific Expression of Group III Metabotropic Glutamate Receptors and Ca2+ Channels in Single Nerve Terminals
RhoG Signals in Parallel with Rac1 and Cdc42RhoG Signals in Parallel with Rac1 and Cdc42
Fas Activation Induces Renal Tubular Epithelial Cell 8 Integrin Expression and Function in the Absence of ApoptosisFas Activation Induces Renal Tubular Epithelial Cell 8 Integrin Expression and Function in the Absence of Apoptosis
Lipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal TransductionLipopolysaccharide Rapidly Traffics to and from the Golgi Apparatus with the Toll-like Receptor 4-MD-2-CD14 Complex in a Process That Is Distinct from the Initiation of Signal Transduction
Carboxyl Terminus of hVIP/mov34 Is Critical for HIV-1-Vpr Interaction and Glucocorticoid-mediated SignalingCarboxyl Terminus of hVIP/mov34 Is Critical for HIV-1-Vpr Interaction and Glucocorticoid-mediated Signaling
Protein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer CellsProtein-tyrosine Phosphatase PTPL1/FAP-1 Triggers Apoptosis in Human Breast Cancer Cells
Phosphorylation of the Catalytic Subunit of Protein Kinase A. AUTOPHOSPHORYLATION VERSUS PHOSPHORYLATION BY PHOSPHOINOSITIDE-DEPENDENT KINASE-1Phosphorylation of the Catalytic Subunit of Protein Kinase A. AUTOPHOSPHORYLATION VERSUS PHOSPHORYLATION BY PHOSPHOINOSITIDE-DEPENDENT KINASE-1
The Pseudokinase Domain Is Required for Suppression of Basal Activity of Jak2 and Jak3 Tyrosine Kinases and for Cytokine-inducible Activation of Signal TransductionThe Pseudokinase Domain Is Required for Suppression of Basal Activity of Jak2 and Jak3 Tyrosine Kinases and for Cytokine-inducible Activation of Signal Transduction
Director Editorial
